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TLR11 Products

TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof.

Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.

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38 results for "TLR11" in Products

38 results for "TLR11" in Products

TLR11 Products

TLRs make up a family of pattern recognition receptors that play important roles in the innate immune response. Broad classes of pathogens (e.g. viruses, bacteria, and fungi) constitutively express a set of mutation-resistant molecules called pathogen-associated molecular patterns (PAMPs). These microbial molecular markers may be composed of proteins, carbohydrates, lipids, nucleic acids and/or combinations thereof.

Individual TLRs recognize distinct pathogen-associated PAMPs, initiating signaling cascades that promote the immune response. Structurally, TLRs are type I transmembrane receptors that possess varying numbers of extracellular N-terminal leucine-rich repeat (LRR) motifs, followed by a cysteine-rich region, a TM domain, and an intracellular Toll/IL-1 R (TIR) motif. The TIR motif is common to the larger IL-1 R/TLR superfamily.

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Source: CHO
Accession #: Q6R5P0
Applications: BA
R&D Systems Recombinant Proteins and Enzymes
Reactivity: Mouse
Details: Rabbit IgG Polyclonal
Applications: WB, ELISA, ICC/IF
Western Blot: TLR11 AntibodyBSA Free [NBP1-77202]
(3)
Applications: AC
Reactivity: Human, Primate, Chimpanzee
Details: Rabbit Polyclonal
Applications: WB, ELISA
Western Blot: TLR11 Antibody [NBP3-12500]
Applications: AC
Applications: AC
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