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10 results for "TIMP-2" in Products
TIMP-2 Products
TIMP-2 (tissue inhibitor of metalloproteinases 2) is one of several TIMPs that form complexes with matrix metalloproteinases (MMPs) and inhibit their proteolytic activity. MMPs play an important role in many normal physiological processes such as embryonic development, morphogenesis, reproduction and tissue remodeling. They also participate in many pathological processes such as arthritis, cancer and cardiovascular disease. TIMP-2 binding to pro-MMP-2 is essential for the cell surface activation of pro-MMP-2 by active MMP-14 (MT1-MMP). TIMP-2 also suppresses EGF-mediated mitogenic signaling by short-circuiting EGF R activation.
Reactivity:
Human, Mouse
Details:
Goat IgG Polyclonal
Applications:
KO, IHC, WB, B/N
Conjugate
Catalog #
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #89025
Applications:
IHC, WB
Conjugate
Catalog #
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #127711
Applications:
KO, ELISA(Cap), ELISA(Det)
Conjugate
Catalog #
Reactivity:
Human, Mouse, Rat, Bovine, Guinea Pig, +2 More
Details:
Mouse IgG2a Kappa Monoclonal Clone #SPM356
Applications:
IHC, WB, Flow, ICC/IF, CyTOF-ready
Conjugate
Catalog #
Forumulation
Catalog #
Reactivity:
Human, Mouse, Rat, Bovine, Guinea Pig, +2 More
Details:
Mouse IgG2a Kappa Monoclonal Clone #3A4
Applications:
IHC, WB, Flow, ICC/IF, CyTOF-ready
Conjugate
Catalog #
Forumulation
Catalog #
Reactivity:
Human, Mouse, Rat, Canine, Monkey
Details:
Mouse IgG1 Monoclonal Clone #OTI1A6
Applications:
IHC, WB, Flow
Conjugate
Catalog #
Forumulation
Catalog #
Recombinant Monoclonal Antibody
Reactivity:
Human, Mouse, Rat, Bovine, Guinea Pig, +2 More
Details:
Rabbit IgG Monoclonal Clone #TIMP2/2488R
Applications:
IHC
Conjugate
Catalog #
Forumulation
Catalog #
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #MM0035-2C13
Applications:
IHC, WB
Conjugate
Catalog #
Forumulation
Catalog #
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #TIMP2/2044
Applications:
IHC, ELISA, Endotoxin
Conjugate
Catalog #
Forumulation
Catalog #
Recombinant Monoclonal Antibody
Reactivity:
Human
Details:
Rabbit IgG Kappa Monoclonal Clone #TIMP2/8193R
Applications:
IHC
Conjugate
Catalog #
Forumulation
Catalog #