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7 results for "TIMP-1" in Products

TIMP-1 Products

TIMP-1 (tissue inhibitor of metalloproteinase-1) is a secreted glycoprotein that blocks metalloproteinase (MMP) activity. It circulates in complex with various MMPs to maintain them in an inactive state. It is produced by fibroblasts, osteoblasts, endothelial cells, granulosa cells, dendritic cells, vascular smooth muscle cells, adipocytes, and monocytes. TIMP-1 also protects against apoptosis in B cells, stimulates erythropoiesis and BFU-E expansion, both stimulates and inhibits tumor growth, inhibits angiogenesis, and stimulates gonadal steroidogenesis in conjuction with Cathepsin L.

Recombinant Monoclonal Antibody

Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #TIMP1/1944R
Applications:
ELISA
Novus Antibodies
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