16 results for "Stem Cell Signaling Compounds Small Molecules and Peptides" in Products

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Stem Cell Signaling Compounds Small Molecules and Peptides

Prostaglandin E2
Catalog #: 2296
(2)
Citations (299)
Product Documents
Images (1)

Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin

Alternate Names:
PGE2
Chemical Name:
(5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid
Purity:
≥98%
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin
Catalog #
Availability
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Qty
2296/10
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IWP 2
Catalog #: 3533
(3)
Citations (547)
Product Documents
Images (2)

PORCN inhibitor; inhibits Wnt processing and secretion

Chemical Name:
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity:
≥98%
iPSC-derived heart organoids differentiated with IWP 2 and CHIR 99021
(2)
Catalog #
Availability
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3533/10
3533/50
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endo-IWR 1
Catalog #: 3532
Citations (71)
Product Documents
Images (1)

Wnt/β-catenin signaling inhibitor; axin stabilizer

Chemical Name:
rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide
Purity:
≥98%
Wnt/β-catenin signaling inhibitor; axin stabilizer
Catalog #
Availability
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Qty
3532/10
3532/50
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XAV 939
Catalog #: 3748
(1)
Citations (410)
Product Documents
Images (1)

Potent tankyrase inhibitor

GMP Version Available: TB3748-GMP
GMP
Alternate Names:
XAV939 Wnt Signaling Inhibitor
Chemical Name:
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity:
≥98%
Potent tankyrase inhibitor
Catalog #
Availability
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Qty
3748/10
3748/50
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Pifithrin-α hydrobromide
Catalog #: 1267
(3)
Citations (14)
Product Documents
Images (1)

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Chemical Name:
1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide
p53 inhibitor. Also aryl hydrocarbon receptor agonist
Catalog #
Availability
Size / Price
Qty
1267/10
1267/50
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Niclosamide
Catalog #: 4079
Citations (10)
Product Documents
Images (1)

STAT3 inhibitor; also inhibits mTORC1 signaling

Chemical Name:
5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
Purity:
≥98%
STAT3 inhibitor; also inhibits mTORC1 signaling
Catalog #
Availability
Size / Price
Qty
4079/50
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XAV 939GMP

Catalog #: TB3748-GMP
Product Documents
Images (1)

XAV 939 synthesized to cGMP guidelines

Chemical Name:
3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
Purity:
≥99%
XAV 939 synthesized to cGMP guidelines
Catalog #
Availability
Size / Price
Qty
TB3748-GMP/10
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Cyclopamine
Catalog #: 1623
(1)
Citations (80)
Product Documents
Images (1)

Inhibitor of Hedgehog (Hh) signaling

Chemical Name:
(2'R,3S,3'R,3'aS,6'S,6aS,6bS,7'aR,11aS,11bR)-1,2,3,3'a,4,4',5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-Octadecahydro-3',6',10,11b-tetramethylspiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-3-ol
Purity:
≥97%
Inhibitor of Hedgehog (Hh) signaling
Catalog #
Availability
Size / Price
Qty
1623/1
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GANT 61
Catalog #: 3191
Citations (55)
Product Documents
Images (1)

GLI antagonist; inhibits Hedgehog (Hh) signaling

Chemical Name:
2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethylbenzenamine
Purity:
≥98%
GLI antagonist; inhibits Hedgehog (Hh) signaling
Catalog #
Availability
Size / Price
Qty
3191/50
3191/10
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BIO
Catalog #: 3194
Citations (85)
Product Documents
Images (1)

Potent GSK-3 inhibitor; also inhibits cdks

Alternate Names:
6BIO
Chemical Name:
(2'Z,3'E)-6-Bromoindirubin-3'-oxime
Purity:
≥98%
Potent GSK-3 inhibitor; also inhibits cdks
Catalog #
Availability
Size / Price
Qty
3194/10
3194/50
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Thiazovivin
Catalog #: 3845
Citations (92)
Product Documents
Images (1)

ROCK inhibitor; improves the efficiency of fibroblast reprogramming and induction of iPSCs

Chemical Name:
N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide
Purity:
≥98%
ROCK inhibitor ; improves the efficiency of fibroblast reprogramming and induction of iPSCs
Catalog #
Availability
Size / Price
Qty
3845/10
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16,16-Dimethyl Prostaglandin E2
Catalog #: 4027
Citations (8)
Product Documents
Images (1)

Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development

Chemical Name:
(5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid
Purity:
≥95%
Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
Catalog #
Availability
Size / Price
Qty
4027/1
Bulk Order

Kenpaullone
Catalog #: 1398
Citations (30)
Product Documents
Images (1)

GSK-3β inhibitor; also inhibits cdks

Chemical Name:
9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one
Purity:
≥98%
GSK-3β inhibitor; also inhibits cdks
Catalog #
Availability
Size / Price
Qty
1398/10
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QS 11
Catalog #: 3324
Citations (7)
Product Documents
Images (1)

ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling

Chemical Name:
(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol
Purity:
≥98%
ARFGAP1 inhibitor; modulates Wnt/β-catenin signaling
Catalog #
Availability
Size / Price
Qty
3324/10
3324/50
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WIKI4
Catalog #: 4855
Citations (5)
Product Documents
Images (1)

Potent tankyrase inhibitor

Chemical Name:
2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione
Purity:
≥98%
Potent tankyrase inhibitor
Catalog #
Availability
Size / Price
Qty
4855/25
4855/5
Bulk Order

NIBR LTSi
Catalog #: 8175
Product Documents
Images (1)

Potent and selective LATS inhibitor; activates YAP signaling

Chemical Name:
N-[4-[(3R)-Piperidin-3-yl]oxyphenyl]-1H-pyrrolo[2,3-b]pyridin-4-amine
Purity:
≥98%
Potent and selective LATS inhibitor; activates YAP signaling
Catalog #
Availability
Size / Price
Qty
8175/50
8175/10
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