Siglec-8 Products
Siglec-8, also known as SAF, is a transmembrane lectin that is expressed on eosinophils, basophils, and mast cells and shows a binding preference for the carbohydrate 6-O sulfated sLe(x). The functional paralog of human Siglec-8 is known as Siglec-F in mouse. Cross-linking of Siglec-8 inhibits Fc epsilon RI alpha-induced mast cell degranulation. It also induces eosinophil apoptosis, an effect that is enhanced by the eosinophil-activating cytokines IL-5, IL-33, and GM-CSF.
Products:
86 results for "Siglec-8" in Products
86 results for "Siglec-8" in Products
Siglec-8 Products
Siglec-8, also known as SAF, is a transmembrane lectin that is expressed on eosinophils, basophils, and mast cells and shows a binding preference for the carbohydrate 6-O sulfated sLe(x). The functional paralog of human Siglec-8 is known as Siglec-F in mouse. Cross-linking of Siglec-8 inhibits Fc epsilon RI alpha-induced mast cell degranulation. It also induces eosinophil apoptosis, an effect that is enhanced by the eosinophil-activating cytokines IL-5, IL-33, and GM-CSF.
Products:
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human, Porcine |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #C1 |
| Applications: | IHC |
| Source: | NS0 |
| Accession #: | AAH53319 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Siglec-8 Antibody [NBP1-31141]](https://resources.bio-techne.com/images/products/Siglec-8-Antibody-Western-Blot-NBP1-31141-img0006.jpg "Western Blot: Siglec-8 Antibody [NBP1-31141]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Siglec-8 Antibody [NBP1-82666]](https://resources.bio-techne.com/images/products/Siglec-8-Antibody-Western-Blot-NBP1-82666-img0005.jpg "Western Blot: Siglec-8 Antibody [NBP1-82666]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #837535 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #7C9 |
| Applications: | ELISA, Flow, IP |
![Flow Cytometry: Siglec-8 Antibody (7C9) - BSA Free [NBP3-05751]](https://resources.bio-techne.com/images/products/Siglec-8-Antibody-7C9-Flow-Cytometry-NBP3-05751-img0001.jpg "Flow Cytometry: Siglec-8 Antibody (7C9) - BSA Free [NBP3-05751]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Siglec-8 Antibody [NBP2-20361]](https://resources.bio-techne.com/images/products/SIGLEC8-Antibody-Western-Blot-NBP2-20361-img0001.jpg "Western Blot: Siglec-8 Antibody [NBP2-20361]")
| Reactivity: | Human, Porcine |
| Details: | Mouse IgG1 kappa Monoclonal Clone #D1 |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: Siglec-8 Antibody [NBP1-06078]](https://resources.bio-techne.com/images/products/Siglec-8-Antibody-Western-Blot-NBP1-06078-img0003.jpg "Western Blot: Siglec-8 Antibody [NBP1-06078]")
| Applications: | ELISA |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #D3 |
| Applications: | WB |
![Western Blot: Siglec-8 Overexpression Lysate [NBP2-07332]](https://resources.bio-techne.com/images/products/SIGLEC8-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-07332-img0001.jpg "Western Blot: Siglec-8 Overexpression Lysate [NBP2-07332]")