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734 results for "Siglec-2/CD22" in Products

Siglec-2/CD22 Products

Siglec-2 (sialic acid binding Ig-like lectin 2), also known as CD22, is a 130-140 kDa type I transmembrane glycoprotein with seven Ig-like domains in the extracellular region and three ITIM motifs in its cytoplasmic region. Alternate splicing generates an additional isoform that lacks the third and fourth Ig-like domains. Siglec-2 is expressed on B cells, preferentially binds alpha 2-6 linked sialic glycans including CD45 and mediates B cell - B cell interactions. Phosphorylation of Tyr822 within one of the ITIMs is important for Siglec-2 signal transduction through its association with the kinases Lyn, PI 3-Kinase p85 alpha, and SYK.

Source: NS0
Accession #: CAA42006
Applications: BA
R&D Systems Recombinant Proteins and Enzymes

Fc Chimera

Source: NS0
Accession #: CAA42006.1
Applications: BA
(2)
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #2H1C4
Applications: IHC, WB, ELISA, ICC/IF, Flow
Western Blot: Siglec-2/CD22 Antibody (2H1C4)BSA Free [NBP2-37327]
(8)
Reactivity: Human, Mouse, Rat, Canine, Monkey
Details: Mouse IgG1 Monoclonal Clone #OTI1F12
Applications: WB, ICC/IF
Western Blot: Siglec-2/CD22 Antibody (OTI1F12) [NBP2-46125]
(5)

Fc Chimera

Source: NS0
Accession #: CAA42006.1
Applications: BA
(2)
Source: CHO
Accession #: CAA42006.1
Applications: BA
Recombinant Human Siglec-2/CD22 His-tag Protein Bioactivity
(2)

Fc Chimera

Source: NS0
Accession #: CAA42006.1
Applications: BA
(2)
Source: HEK293
Accession #: EHH59463
Applications: BA
Recombinant Cynomolgus Siglec-2/CD22 His-tag Protein Bioactivity
(2)
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #219934
Applications: Flow, CyTOF-ready
Detection of Siglec-2/CD22 antibody in Human PBMCs antibody by Flow Cytometry.

Biotinylated

Source: CHO
Accession #: CAA42006.1
Applications: BA, BA
(2)

Biotinylated

Source: CHO
Accession #: CAA42006.1
Applications: BA, BA
(2)

Recombinant Monoclonal Antibody. His-tagged VHH domain.

Reactivity: Human
Details: Llama Monoclonal Clone #L007.2.5N
Applications: Flow, ICC
(2)

Recombinant Monoclonal Antibody. Bivalent Llama VHH domain, Human IgG2 Fusion Antibody.

Reactivity: Human
Details: Llama Monoclonal Clone #L007.2.5H
Applications: IHC, ICC
(2)
Source: NS0
Accession #: P35329
Applications: BA
R&D Systems Recombinant Proteins and Enzymes

Fc Chimera

Source: NS0
Accession #: CAA42006.1
Applications: BA
(2)
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