788 results for "Siglec-2/CD22" in Products
Siglec-2/CD22 Products
Siglec-2 (sialic acid binding Ig-like lectin 2), also known as CD22, is a 130-140 kDa type I transmembrane glycoprotein with seven Ig-like domains in the extracellular region and three ITIM motifs in its cytoplasmic region. Alternate splicing generates an additional isoform that lacks the third and fourth Ig-like domains. Siglec-2 is expressed on B cells, preferentially binds alpha 2-6 linked sialic glycans including CD45 and mediates B cell - B cell interactions. Phosphorylation of Tyr822 within one of the ITIMs is important for Siglec-2 signal transduction through its association with the kinases Lyn, PI 3-Kinase p85 alpha, and SYK.
| Source: | HEK293 |
| Accession #: | EHH59463 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | CAA42006 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P35329 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | CAA42006.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | CAA42006.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #219903 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219902 |
| Applications: | WB |
Conjugate
Catalog #
| Source: | CHO |
| Accession #: | CAA42006.1 |
| Applications: | BA, BA |
| Source: | CHO |
| Accession #: | CAA42006.1 |
| Applications: | BA, BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #219903 |
| Applications: | Neut |
Conjugate
Catalog #
| Source: | NS0 |
| Accession #: | CAA42006.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219933 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219933 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219902 |
Human Siglec-2/CD22 LlamabodyTM VHH His-tag Alexa Fluor™ Plus 680-conjugated Antibody
Catalog #:
LFAB10732AFP680
| Reactivity: | Human |
| Details: | Llama Monoclonal Clone #L007.2.5N |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219934 |
Human Phospho-Siglec-2/CD22 (Y822) Alexa Fluor™ Plus 488-conjugated Antibody
Catalog #:
FAB7290AFP488
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #726830 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219933 |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #308501 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #219933 |