3 results for "Retinoic Acid Receptor Antagonists" in Products
Retinoic Acid Receptor Antagonists Products
Retinoic acid receptors (RARs) are nuclear hormone receptors of the NR1B class, which function as heterodimers with retinoid X receptors (RXRs). There are three distinct RAR subtypes: RARα, RARβ and RARγ. RARα is present in most tissue types, whereas RARβ and RARγ expression is more selective.
RXR-RAR heterodimers act as ligand-dependent transcriptional regulators by binding to the specific retinoic acid response element (RARE) found in the promoter regions of ...
High affinity pan-RAR antagonist
| Chemical Name: | 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
Selective RARα antagonist
| Chemical Name: | 4-[5-[8-(1-Methylethyl)-4-phenyl-2-quinolinyl]-1H-pyrrolo-2-benzoic acid |
| Purity: | ≥98% (HPLC) |
Selective RARβ/γ antagonist
| Chemical Name: | 4-[6-[(2-Methoxyethoxy)methoxy]-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid |
| Purity: | ≥98% (HPLC) |
