Skip to main content

12 results for "ras-gtpase-inhibitors&view=expanded" in Products

Potent farnesyl diphosphate (FPP) synthase inhibitor

Alternate Names:
Zometa
Chemical Name:
[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Purity:
≥98%
Potent farnesyl diphosphate (FPP) synthase inhibitor

Potent Rac family inhibitor

Chemical Name:
5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride
Purity:
≥98%
Potent Rac family inhibitor

Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Chemical Name:
[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone
Purity:
≥98%
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker

Chemical Name:
N-(3,3-Diphenylpropyl)-α-methylbenzylamine hydrochloride
Purity:
≥98%
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker

Ras signaling inhibitor; inhibits Ack1 and GCK

Chemical Name:
N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Purity:
≥98%
Ras signaling inhibitor; inhibits Ack1 and GCK

High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ

Chemical Name:
2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole trihydrochloride
Purity:
≥98%
High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ

Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor

Chemical Name:
4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide
Purity:
≥98%
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor

Potent and selective KRASG12C inhibitor

Alternate Names:
Sotorasib
Chemical Name:
(1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one
Purity:
≥98%
Potent and selective KRASG12C inhibitor

Mutation-selective inhibitor of KRASG12C

Alternate Names:
Adagrasib
Chemical Name:
4-[7-(8-Chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoro-1-oxo-2-propen-1-yl)-(2S)-2-piperazineacetonitrile
Purity:
≥98%
Mutation-selective inhibitor of KRASG12C

Potent covalent inhibitor of the RAS domain of the PI3K/p110α interaction

Chemical Name:
5-((1R,2S,5S)-2-(2-Chloro-3-fluorophenyl)-3-azabicyclo[3.1.0]hexan-3-yl)-N-((R,E)-4-(methylsulfonyl)but-3-en-2-yl)pyrazine-2-carboxamide
Purity:
≥98%
Potent covalent inhibitor of the RAS domain of the PI3K/p110α interaction
Results Per Page
5 10 25 50