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8 results for "Ras GTPase Inhibitors" in Products
Ras GTPase Inhibitors
Potent farnesyl diphosphate (FPP) synthase inhibitor
Alternate Names:
Zometa
Chemical Name:
[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Purity:
≥98%
Inhibits KRas localization to the plasma membrane; also L-type calcium channel blocker
Chemical Name:
N-(3,3-Diphenylpropyl)-α-methylbenzylamine hydrochloride
Purity:
≥98%
Ras signaling inhibitor; inhibits Ack1 and GCK
Chemical Name:
N-[3-[1,4-Dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trifluoromethyl)benzamide
Purity:
≥98%
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
Chemical Name:
[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone
Purity:
≥98%
Leucyl-tRNA synthase (TRS)/Ras-related GTP-binding protein D (RagD) interaction inhibitor
Chemical Name:
4-[2,5-Dihydro-2,3-dimethyl-4-(1-methylethyl)-5-oxo-1H-pyrazol-1-yl]-N-(2-phenoxyethyl)benzenesulfonamide
Purity:
≥98%
Mutation-selective inhibitor of KRASG12C
Alternate Names:
Adagrasib
Chemical Name:
4-[7-(8-Chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoro-1-oxo-2-propen-1-yl)-(2S)-2-piperazineacetonitrile
Purity:
≥98%
Potent and selective KRASG12C inhibitor
Alternate Names:
Sotorasib
Chemical Name:
(1R)-6-Fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-[4-methyl-2-(1-methylethyl)-3-pyridinyl]-4-[(2S)-2-methyl-4-(1-oxo-2-propen-1-yl)-1-piperazinyl]pyrido[2,3-d]pyrimidin-2(1H)-one
Purity:
≥98%
Pan RAS Tracer
Chemical Name:
N-(15-(5,5-Difluoro-7-(1H-pyrrol-2-yl)-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-13-oxo-3,6,9-trioxa-12-azapentadecyl)-5-(2-((6-((((3-(6-hydroxy-3-oxoisoindolin-1-yl)-1H-indol-2-yl)methyl)amino)methyl)-1H-indol-1-yl)methyl)-1H-imidazol-1-yl)pentanamide
Purity:
≥95%
