2 results for "RAGE/AGER Small Molecules and Peptides" in Products
RAGE/AGER: Small Molecules and Peptides
RAGE (Receptor for Advanced Glycation End product) is a transmembrane glycoprotein that binds advanced glycation end products (AGEs), beta-amyloid peptides, HMGB1/Amphoterin, and several S100 family proteins. AGEs are adducts formed by the non-enzymatic glycation and oxidation of proteins and lipids. A soluble form can also be generated by MMP-mediated shedding. RAGE is expressed in the CNS during development as well as in adult endothelial cells, smooth muscle cells, pericytes, monocytes, and ...
ctRAGE-DIAPH1 interaction antagonist; reduces inflammatory signaling in diabetic mice
| Chemical Name: | N-[4-[7-Cyano-4-(4-morpholinylmethyl)-2-quinolinyl]phenyl]acetamide |
| Purity: | ≥98% (HPLC) |
High affinity antagonist of RAGE
| Chemical Name: | 4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide |
| Purity: | ≥98% (HPLC) |
