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10 results for "R-Spondin 1 Proteins and Enzymes" in Products
R-Spondin 1 Proteins and Enzymes
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
Reactivity:
Human
Source:
CHO
Accession #:
Q2MKA7
Applications:
Bioactivity
Reactivity:
Mouse
Source:
CHO
Accession #:
NP_619624
Applications:
Bioactivity
Reactivity:
Mouse
Source:
E. coli
Accession #:
Q9Z132
Applications:
Bioactivity
Reactivity:
Mouse
Source:
CHO
Applications:
Bioactivity
Reactivity:
Human
Source:
E. coli
Accession #:
Q2MKA7.1
Applications:
Bioactivity
Biotinylated
Reactivity:
Human
Source:
CHO
Accession #:
Q2MKA7.1
Applications:
Bioactivity
Reactivity:
Human
Source:
CHO
Accession #:
Q2MKA7
Applications:
Bioactivity
Catalog #:
NBP1-92357PEP
Reactivity:
Human
Source:
E. coli
Applications:
AC
Catalog #:
NBP3-21297PEP
Reactivity:
Human
Source:
E. coli
Applications:
AC
Catalog #:
NBP1-77354PEP
Reactivity:
Human
Source:
Synthetic
Applications:
AC