7 results for "Proteasome Inhibitors Small Molecules and Peptides" in Products
Proteasome Inhibitors: Small Molecules and Peptides
The proteasome complex is a broad spectrum protease present in all eukaryotes, which functions to carry out selective, efficient and progressive hydrolysis of intracellular target proteins. The proteasome plays a prominent role in the control of a diverse array of basic cellular processes by rapidly catalyzing numerous biological reactions.
The proteasome complex is composed of a 20S catalytic core and one or two terminal 19S regulatory units. The 20S catalytic domain is barrel-shaped and ...
High affinity proteasome inhibitor
| Chemical Name: | B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid |
| Purity: | ≥98% (HPLC) |
Proteasome and calpain inhibitor. Inhibits NF-κB activation
| Alternate Names: | Z-LLL-al,Z-Leu-Leu-Leu-CHO |
| Chemical Name: | N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-L-leucinamide |
| Purity: | ≥95% (HPLC) |
Potent 20S proteasome inhibitor
| Chemical Name: | N-[(Phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-D-leucinamide |
| Purity: | ≥98% (HPLC) |
Cell-permeable, potent and selective proteasome inhibitor
| Chemical Name: | (2R,3S,4R)-3-Hydroxy-2-[(1S)-1-hydroxy-2-methylpropyl]-4-methyl-5-oxo-2-pyrrolidinecarboxy-N-acetyl-L-cysteine thioester |
| Purity: | ≥95% (HPLC) |
Potent irreversible proteasome inhibitor; active in vivo
| Alternate Names: | PR-171 |
| Chemical Name: | (αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide |
| Purity: | ≥98% (HPLC) |
Selective proteasome inhibitor
| Chemical Name: | 8,8'-Dithiobis[N-[2-(2-thiazolyl)ethyl]-3-quinolinecarboxamide] |
| Purity: | ≥98% (HPLC) |
