PP2C epsilon/PPM1L Products
PP2C epsilon, also known as PPM1L, is a 34 kDa (predicted) widely expressed Ser/Thr phosphatase. It consists of a 25 amino acid (aa) extracellular domain, a 17 aa transmembrane segment, and a 318 aa cytoplasmic region (aa 43-360) which contains the phosphatase domain (aa 91-344). Alternate splicing generates additional isoforms of human PP2C epsilon with 179 aa or 127 aa N-terminal truncations or a 166 aa C-terminal truncation. The PP2C epsilon-mediated dephosphorylation of TAK1 and ASK1 is regulated by oxidative stress and inflammatory cytokines. Loss of PP2C epsilon function is associated with the development of metabolic syndrome.
39 results for "PP2C epsilon/PPM1L" in Products
39 results for "PP2C epsilon/PPM1L" in Products
PP2C epsilon/PPM1L Products
PP2C epsilon, also known as PPM1L, is a 34 kDa (predicted) widely expressed Ser/Thr phosphatase. It consists of a 25 amino acid (aa) extracellular domain, a 17 aa transmembrane segment, and a 318 aa cytoplasmic region (aa 43-360) which contains the phosphatase domain (aa 91-344). Alternate splicing generates additional isoforms of human PP2C epsilon with 179 aa or 127 aa N-terminal truncations or a 166 aa C-terminal truncation. The PP2C epsilon-mediated dephosphorylation of TAK1 and ASK1 is regulated by oxidative stress and inflammatory cytokines. Loss of PP2C epsilon function is associated with the development of metabolic syndrome.
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: PP2C epsilon/PPM1L Antibody [NBP1-87248]](https://resources.bio-techne.com/images/products/PP2C-epsilon-PPM1L-Antibody-Western-Blot-NBP1-87248-img0006.jpg "Western Blot: PP2C epsilon/PPM1L Antibody [NBP1-87248]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: PP2C epsilon/PPM1L Antibody [NBP1-87247]](https://resources.bio-techne.com/images/products/PP2C-epsilon-PPM1L-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-87247-img0007.jpg "Immunocytochemistry/ Immunofluorescence: PP2C epsilon/PPM1L Antibody [NBP1-87247]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
![Western Blot: PP2C epsilon/PPM1L Antibody [NBP2-88077]](https://resources.bio-techne.com/images/products/PP2C-epsilon-PPM1L-Antibody-Western-Blot-NBP2-88077-img0001.jpg "Western Blot: PP2C epsilon/PPM1L Antibody [NBP2-88077]")
| Applications: | WB |
![Western Blot: PP2C epsilon/PPM1L Overexpression Lysate [NBL1-14666]](https://resources.bio-techne.com/images/products/PPM1L-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-14666-img0002.jpg "Western Blot: PP2C epsilon/PPM1L Overexpression Lysate [NBL1-14666]")
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #700612 |
| Applications: | WB |
Substrate for Calcineurin, PP1, PP2A, PP2C, and Ser/Thr phosphatases
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #700612 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #700612 |
| Applications: | WB |