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82 results for "PP1 Inhibitor-2" in Products

PP1 Inhibitor-2 Products

Protein Phosphatase 1 Inhibitor-2 (PP1 Inhibitor-2), also called PP1 regulatory subunit 2 (PP1R2), I2, and IPP2, binds to PP1 through an RVxF consensus sequence. The complex inactivates PP1, preventing it from dephosphorylating substrates such as glycogen phosphorylase. Unlike PP1 Inhibitor-1, the binding of PP1 Inhibitor-2 is Protein Kinase A phosphorylation-independent. Dissociation of the PP1 Inhibitor-2 complex is enhanced by phosphorylation at T72 by GSK-3, ERK, or CDK. Overexpression of PP1 Inhibitor-2 in mouse heart improves cardiac function without changing organ size.

Catalog #: AF4719AFP680
Catalog #: AF4719AFP405
Catalog #: AF4719AFP555
Catalog #: AF4719AFP488
Catalog #: AF4719AFP594
Catalog #: AF4719AFP647
Catalog #: FAB4719AFP594
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