PDGF-DD Products
Platelet-derived growth factor-D (PDGF-D) is a cytokine that associates into disulfide-linked homodimers that bind to PDGF R beta and trigger signaling through PDGF R beta homodimers and PDGF R alpha/beta heterodimers. It is secreted as a latent homodimer which is activated by proteolysis to release a bioactive disulfide-linked dimer. PDGF-DD is widely expressed in embryonic and adult tissues.
It functions as a growth factor for renal artery smooth muscle cells and lens epithelial cells and as a macrophage chemoattractant. PDGF-DD is upregulated in and contributes to several disease states, including renal and hepatic fibrosis, mesangial proliferative glomerulopathy, pulmonary lymphoid infiltration, and many cancers.
Products:
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PDGF-DD Products
Platelet-derived growth factor-D (PDGF-D) is a cytokine that associates into disulfide-linked homodimers that bind to PDGF R beta and trigger signaling through PDGF R beta homodimers and PDGF R alpha/beta heterodimers. It is secreted as a latent homodimer which is activated by proteolysis to release a bioactive disulfide-linked dimer. PDGF-DD is widely expressed in embryonic and adult tissues.
It functions as a growth factor for renal artery smooth muscle cells and lens epithelial cells and as a macrophage chemoattractant. PDGF-DD is upregulated in and contributes to several disease states, including renal and hepatic fibrosis, mesangial proliferative glomerulopathy, pulmonary lymphoid infiltration, and many cancers.
Products:
| Sensitivity: | 3.51 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.3 - 2,000 pg/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Saliva, Human Milk) |
| Source: | NS0 |
| Accession #: | Q9GZP0.1 |
| Applications: | BA |
| Applications: | ELISA, Ctrl |
| Assay Range: | 7.81 - 500 pg/mL |
| Applications: | ELISA |
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