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13 results for "PD-1" in Products
PD-1 Products
PD-1 (Programmed Death-1 receptor) is a key regulator of the threshold of immune response and peripheral immune tolerance. It is expressed on activated T cells, B cells, monocytes, and dendritic cells and binds to PD-L1 or PD-L2. PD-1 ligation induces co-inhibitory signals in T cells promoting their apoptosis, anergy, and functional exhaustion. Many tumors overexpress PD-L1 to induce this inhibitory signaling pathway in immune cells. When PD-1 expressing immune cells come into contact with a ...
Analyzed by SEC-MALS
Reactivity:
Human
Source:
HEK293
Accession #:
Q15116.3
Applications:
Bioactivity
Reactivity:
Mouse
Source:
NS0
Accession #:
Q02242
Applications:
Bioactivity
Reactivity:
Cynomolgus Monkey
Source:
HEK293
Accession #:
NP_001271065.1
Applications:
Bioactivity
Reactivity:
Porcine
Source:
CHO
Accession #:
NP_001191308.1
Applications:
Bioactivity
Reactivity:
Porcine
Source:
CHO
Accession #:
NP_001191308.1
Applications:
Bioactivity
Reactivity:
Canine
Source:
HEK293
Accession #:
NP_001301026.1
Applications:
Bioactivity
Reactivity:
Rat
Source:
NS0
Accession #:
NP_001100397
Applications:
Bioactivity
Biotinylated
Reactivity:
Human
Source:
HEK293
Accession #:
Q15116.3
Applications:
Bioactivity
Reactivity:
Cynomolgus Monkey
Source:
HEK293
Accession #:
NP_001271065
Applications:
Bioactivity
Reactivity:
Human
Source:
NS0
Accession #:
Q15116.3
Applications:
Bioactivity
Reactivity:
Human
Source:
NS0
Accession #:
Q15116.3
Applications:
Bioactivity
Reactivity:
Human
Source:
NS0
Accession #:
Q15116.3
Applications:
Bioactivity
Biotinylated
Reactivity:
Human
Source:
CHO
Accession #:
Q15116.3
Applications:
Bioactivity
