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Nectin-2/CD112 Products
Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Homology has led to their designation as poliovirus receptor-related (PRR) proteins, but nectins do not bind poliovirus. The extracellular domains of the nectin family form cis-homodimers (same cell), followed by homophilic or heterophilic trans-dimers (across cells) that organize intercellular junctions. Nectin-1, also known as CD111, PRR1 and herpes virus entry mediator C (HVEC) has a secreted splice variant. Nectin-1, Nectin-2 (CD112, PRR2, HVEB) and Nectin-3 (PRR3) are concentrated in adherens junctions and exist on neurons, endothelial cells, epithelial cells and fibroblasts. Nectin-4 is mainly expressed in the placenta; a soluble form is generated via the action of TACE/ADAM17.
38 results for "Nectin-2/CD112" in Products
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Nectin-2/CD112 Products
Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Homology has led to their designation as poliovirus receptor-related (PRR) proteins, but nectins do not bind poliovirus. The extracellular domains of the nectin family form cis-homodimers (same cell), followed by homophilic or heterophilic trans-dimers (across cells) that organize intercellular junctions. Nectin-1, also known as CD111, PRR1 and herpes virus entry mediator C (HVEC) has a secreted splice variant. Nectin-1, Nectin-2 (CD112, PRR2, HVEB) and Nectin-3 (PRR3) are concentrated in adherens junctions and exist on neurons, endothelial cells, epithelial cells and fibroblasts. Nectin-4 is mainly expressed in the placenta; a soluble form is generated via the action of TACE/ADAM17.
38 results for "Nectin-2/CD112" in Products
Design and order Simple Plex cartridges tailor made to meet your needs with customizable Simple Plex Assay panels for the Ella platform.
| Assay Range : | 78.1 - 5,000 pg/mL |
| Applications : | ELISA |
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #610611 |
| Applications : | Block/Neutralize, Immunocytochemistry/Immunofluorescence |
| Clonality : | Monoclonal |
| Host : | Mouse IgG2b Clone #610615 |
| Applications : | Block/Neutralize |
Biotinylated
| Source : | CHO |
| Accession # : | NP_002847.1 |
| Applications : | Bioactivity |
| Clonality : | Polyclonal |
| Host : | Goat IgG |
| Applications : | Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Simple Western, Western Blot |
Simple Plex Human Nectin-2/CD112 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Biotinylated
| Source : | HEK293 |
| Accession # : | NP_002847.1 |
| Applications : | Bioactivity |
| Source : | CHO |
| Accession # : | XP_005589607.1 |
| Applications : | Bioactivity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #610603 |
| Applications : | Flow Cytometry, Immunocytochemistry/Immunofluorescence |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #829038 |
| Applications : | CyTOF-ready, Flow Cytometry |
| Clonality : | Polyclonal |
| Host : | Sheep IgG |
| Applications : | Western Blot |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #610603 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #610603 |
| Applications : | Flow Cytometry |
| Source : | HEK293 |
| Accession # : | NP_002847.1 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | NP_002847 |
| Applications : | Binding Activity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #610603 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #829038 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #610603 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #610603 |
| Applications : | Flow Cytometry |
| Source : | CHO |
| Accession # : | XP_005589607.1 |
| Applications : | Bioactivity |
| Source : | NS0 |
| Accession # : | P32507 |
| Applications : | Binding Activity |
| Clonality : | Monoclonal |
| Host : | Mouse IgG1 Clone #610603 |
| Applications : | Flow Cytometry |
| Clonality : | Monoclonal |
| Host : | Rat IgG2a Clone #829038 |
| Applications : | Flow Cytometry |
