MMP-12 Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
92 results for "MMP-12" in Products
92 results for "MMP-12" in Products
MMP-12 Products
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Applications: | NULL |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR03-23 |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Western Blot: MMP-12 Antibody (SR03-23) [NBP2-67344]](https://resources.bio-techne.com/images/products/MMP-12-Antibody-SR03-23-Western-Blot-NBP2-67344-img0005.jpg "Western Blot: MMP-12 Antibody (SR03-23) [NBP2-67344]")
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MMP-12 Antibody [NBP1-31225]](https://resources.bio-techne.com/images/products/MMP-12-Antibody-Western-Blot-NBP1-31225-img0015.jpg "Western Blot: MMP-12 Antibody [NBP1-31225]")
| Source: | NS0 |
| Accession #: | P39900 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82902 |
| Applications: | WB, IHC, IP, AP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, IP |
| Source: | NS0 |
| Accession #: | EDL24933 |
| Applications: | EnzAct |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82902 |
| Applications: | WB, IHC, IP, AP |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82902 |
| Applications: | WB, IHC, IP, AP |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82902 |
| Applications: | WB, IHC, IP, AP |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #82902 |
| Applications: | WB, IHC, IP, AP |
| Source: | NS0 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, IP |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, IP |
| Chemical Name: | (βR)-β-[[[(1S)-1-[[[(1S)-2-Methoxy-1-phenylethyl]amino]carbonyl]-2,2-dimethylpropyl]amino]carbonyl]-2-methyl-[1,1'-biphenyl]-4-hexanoic acid |
| Purity: | ≥95% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #706F9.01 |
| Applications: | IHC, WB, ELISA, IP |
![Immunohistochemistry: MMP-12 Antibody (706F9.01) [DDX0281P-100]](https://resources.bio-techne.com/images/products/MMP-12-Antibody-706F9-01-Immunohistochemistry-DDX0281P-100-img0004.jpg "Immunohistochemistry: MMP-12 Antibody (706F9.01) [DDX0281P-100]")
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |