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12 results for "MDM2/HDM2" in Products
MDM2/HDM2 Products
MDM2 is a key regulator of p53 tumor suppressor protein activity and stability. MDM2 binds to and inhibits the transactivation domain of p53. In addition, MDM2 controls p53 stability by functioning as its E3 ligase in ubiquitination and by shuttling p53 from the nucleus to the cytoplasm for subsequent degradation. The importance of the p53/MDM2 relationship is underscored by the existence of an autoregulatory feedback loop whereby activated p53 transcriptionally upregulates the expression of its own inhibitor, MDM2.
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 kappa Monoclonal Clone #SMP14
Applications:
IHC, WB, IP
Conjugate
Catalog #
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
Conjugate
Catalog #
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #197702
Applications:
IP
Conjugate
Catalog #
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
WB, ELISA, IP
Conjugate
Catalog #
Forumulation
Catalog #
Reactivity:
Human, Mouse
Details:
Mouse IgG2A Monoclonal Clone #HDM2-323
Applications:
WB, ELISA
Conjugate
Catalog #
Forumulation
Catalog #
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #2G2 2.2
Applications:
WB, IP
Conjugate
Catalog #
Forumulation
Catalog #
Recombinant Monoclonal Antibody
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #MDM2/7061R
Applications:
ELISA
Conjugate
Catalog #
Forumulation
Catalog #
Reactivity:
Human
Details:
Mouse IgG2 kappa Monoclonal Clone #MDM2/7942
Applications:
IHC
Conjugate
Catalog #
Forumulation
Catalog #
Reactivity:
Human
Details:
Mouse IgG2 kappa Monoclonal Clone #MDM2/8221
Applications:
IHC
Conjugate
Catalog #
Forumulation
Catalog #
Recombinant Monoclonal Antibody
Reactivity:
Human
Details:
Rabbit IgG Kappa Monoclonal Clone #MDM2/7190R
Applications:
IHC
Conjugate
Catalog #
Forumulation
Catalog #
Recombinant Monoclonal Antibody
Reactivity:
Human
Details:
Rabbit IgG Kappa Monoclonal Clone #MDM2/7189R
Applications:
IHC
Conjugate
Catalog #
Forumulation
Catalog #
Recombinant Monoclonal Antibody
Reactivity:
Human
Details:
Mouse IgG2b Kappa Monoclonal Clone #rMDM2/9214
Applications:
IHC
Conjugate
Catalog #
Forumulation
Catalog #