MafA Products
Insulin gene expression is regulated by several islet-enriched transcription factors. However, MafA is the only beta cell-specific activator. MafA selectively induces endogenous insulin transcription in non-beta cells. MafA was also first detected in the insulin-producing cells formed during the second and predominant phase of beta cell differentiation, and absent in the few insulin-positive cells found in Nkx6.1(-/-) pancreata, which lack the majority of second-phase beta cells. These results demonstrate that MafA is a potent insulin activator that is likely to function downstream of Nkx6.1 during islet insulin-producing cell development.
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37 results for "MafA" in Products
37 results for "MafA" in Products
MafA Products
Insulin gene expression is regulated by several islet-enriched transcription factors. However, MafA is the only beta cell-specific activator. MafA selectively induces endogenous insulin transcription in non-beta cells. MafA was also first detected in the insulin-producing cells formed during the second and predominant phase of beta cell differentiation, and absent in the few insulin-positive cells found in Nkx6.1(-/-) pancreata, which lack the majority of second-phase beta cells. These results demonstrate that MafA is a potent insulin activator that is likely to function downstream of Nkx6.1 during islet insulin-producing cell development.
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, GS |
![Western Blot: MafA Antibody [NB400-137]](https://resources.bio-techne.com/images/products/MafA-Antibody-Western-Blot-NB400-137-img0008.jpg "Western Blot: MafA Antibody [NB400-137]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: MafA Antibody [NBP1-00121]](https://resources.bio-techne.com/images/products/MafA-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-00121-img0003.jpg "Immunocytochemistry/ Immunofluorescence: MafA Antibody [NBP1-00121]")
| Reactivity: | Human, Mouse, Rat, Opossum |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, ICC/IF (-) |
![Western Blot: MafA Antibody [NBP2-24636]](https://resources.bio-techne.com/images/products/MafA-Antibody-Western-Blot-NBP2-24636-img0001.jpg "Western Blot: MafA Antibody [NBP2-24636]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #BLR067G |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: MafA Antibody (BLR067G) [NBP2-78707]](https://resources.bio-techne.com/images/products/MafA-Antibody-BLR067G-NBP2-78707-img0007.jpg "Western Blot: MafA Antibody (BLR067G) [NBP2-78707]")
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
![Western Blot: MafA Antibody [NBP3-09249]](https://resources.bio-techne.com/images/products/MafA-Antibody-Western-Blot-NBP3-09249-img0001.jpg "Western Blot: MafA Antibody [NBP3-09249]")
| Applications: | WB, ELISA, MA, AP |
![Western Blot: MafA Overexpression Lysate [NBP2-04601]](https://resources.bio-techne.com/images/products/MafA-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-04601-img0001.jpg "Western Blot: MafA Overexpression Lysate [NBP2-04601]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, GS |
![MafA Antibody [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nb400-137cl1_rabbit-mafa-pab-corafluor-1-10920251141213.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, GS |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, GS |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, GS |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, GS |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, GS |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF, ChIP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, GS |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, ChIP, GS |