4 results for "LRRK2 Inhibitors" in Products
LRRK2 Inhibitors Products
Leucine-rich repeat kinase 2 (LRRK2 or RIP7) is a large multidomain protein kinase that includes leucine-rich repeats and a GTPase domain. It is a member of the receptor interacting protein kinase family.
The biological function and regulation of LRRK2 is poorly understood, however, the enzyme is constitutively expressed in neurons and glial cells and is associated with certain neurodegenerative diseases. Autosomal dominant missense mutations in LRRK2 are commonly associated with late-onset ...
Potent and selective LRRK2 inhibitor
| Chemical Name: | 5,11-Dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% |
Potent and selective LRRK2 inhibitor
| Chemical Name: | rel-3-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-pyrimidyl]-5-[(1-methylcyclopropyl)oxy]-1H-indazole |
| Purity: | ≥98% (HPLC) |
Potent LRRK2 inhibitor
| Chemical Name: | N-[2-[[5-Fluoro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide |
| Purity: | ≥98% (HPLC) |
Potent and selective LRRK2 inhibitor
| Chemical Name: | [4-[[5-Chloro-4-(methylamino)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxyphenyl]-4-morpholinyl-methanone |
| Purity: | ≥98% (HPLC) |
