LRH-1/NR5A2 Products
Liver receptor homolog-1 (LRH-1, FTF, CPF, hB1F, FTZ-F1b; NR5A2) is a member of the orphan nuclear receptor family. LRH-1 is a mammalian homolog of the Drosophila fushi tarazu Factor 1 gene product. LRH-1 is thought to be critical for development because LRH-1 knockout mice are not viable. LRH-1 is expressed in the liver, intestine, pancrease, ovary and preadipocytes.
LRH-1 is involved in the regulation of genes which participate in steroid, bile acid and cholesterol homeostasis. A role for LRH-1 in steroidogenesis is supported by its expression in ovarian granulosa cells and corpus luteum. LRH-1 has been shown to regulate transcription of several steroidogenic genes and is known to modulate the expression of aromatase in breast adipose tissue.
77 results for "LRH-1/NR5A2" in Products
77 results for "LRH-1/NR5A2" in Products
LRH-1/NR5A2 Products
Liver receptor homolog-1 (LRH-1, FTF, CPF, hB1F, FTZ-F1b; NR5A2) is a member of the orphan nuclear receptor family. LRH-1 is a mammalian homolog of the Drosophila fushi tarazu Factor 1 gene product. LRH-1 is thought to be critical for development because LRH-1 knockout mice are not viable. LRH-1 is expressed in the liver, intestine, pancrease, ovary and preadipocytes.
LRH-1 is involved in the regulation of genes which participate in steroid, bile acid and cholesterol homeostasis. A role for LRH-1 in steroidogenesis is supported by its expression in ovarian granulosa cells and corpus luteum. LRH-1 has been shown to regulate transcription of several steroidogenic genes and is known to modulate the expression of aromatase in breast adipose tissue.
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #PCRP-NR5A2-1B8 |
| Applications: | IHC, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #PCRP-NR5A2-1B8 |
| Applications: | IHC, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #PCRP-NR5A2-1B8 |
| Applications: | IHC, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #PCRP-NR5A2-1B8 |
| Applications: | IHC, Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #PCRP-NR5A2-1B8 |
| Applications: | IHC, Flow |
![LRH-1/NR5A2 Antibody (PCRP-NR5A2-1B8) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp3-26934cl1_mouse-lrh-1-nr5a2-mab-pcrp-nr5a2-1b8-corafluor-1-291020251216341.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Mouse IgG3 Monoclonal Clone #H2325 |
| Applications: | WB, IP, DirELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3H8 |
| Applications: | IHC, WB |
![Western Blot: LRH-1/NR5A2 Antibody (OTI3H8) [NBP2-46248]](https://resources.bio-techne.com/images/products/LRH-1-NR5A2-Antibody-3H8-Western-Blot-NBP2-46248-img0002.jpg "Western Blot: LRH-1/NR5A2 Antibody (OTI3H8) [NBP2-46248]")
| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +10 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Mycoplasma |
![Western Blot: LRH-1/NR5A2 Antibody [NBP2-27196]](https://resources.bio-techne.com/images/products/LRH-1-NR5A2-Antibody-Western-Blot-NBP2-27196-img0004.jpg "Western Blot: LRH-1/NR5A2 Antibody [NBP2-27196]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: LRH-1/NR5A2 Antibody [NBP1-32489]](https://resources.bio-techne.com/images/products/LRH-1-NR5A2-Antibody-Western-Blot-NBP1-32489-img0007.jpg "Western Blot: LRH-1/NR5A2 Antibody [NBP1-32489]")
| Reactivity: | Human, Canine, Primate, Chicken, Feline, +3 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western |
![Western Blot: LRH-1/NR5A2 Antibody [NBP2-27204]](https://resources.bio-techne.com/images/products/LRH-1-NR5A2-Antibody-Western-Blot-NBP2-27204-img0003.jpg "Western Blot: LRH-1/NR5A2 Antibody [NBP2-27204]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3H8 |
| Applications: | IHC, WB |
![Western Blot: LRH-1/NR5A2 Antibody (OTI3H8)Azide and BSA Free [NBP2-72521]](https://resources.bio-techne.com/images/products/LRH-1-NR5A2-Antibody-OTI3H8-Azide-and-BSA-Free-Western-Blot-NBP2-72521-img0001.jpg "Western Blot: LRH-1/NR5A2 Antibody (OTI3H8)Azide and BSA Free [NBP2-72521]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #K8801 |
| Applications: | WB, IP |
| Reactivity: | Human, Porcine |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: LRH-1/NR5A2 Antibody [NBP2-42513]](https://resources.bio-techne.com/images/products/LRH-1-NR5A2-Antibody-Western-Blot-NBP2-42513-img0004.jpg "Western Blot: LRH-1/NR5A2 Antibody [NBP2-42513]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR2100 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE30-50 |
| Applications: | WB |
| Applications: | WB |
![Western Blot: LRH-1/NR5A2 Overexpression Lysate [NBP2-04258]](https://resources.bio-techne.com/images/products/NR5A2-LRH1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-04258-img0001.jpg "Western Blot: LRH-1/NR5A2 Overexpression Lysate [NBP2-04258]")
| Applications: | ELISA |
| Applications: | ELISA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3H8 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3H8 |
| Applications: | IHC, WB |
![LRH-1/NR5A2 Antibody (OTI3H8) [CoraFluor™ 1]](https://resources.bio-techne.com/images/products/nbp2-72521cl1_mouse-lrh-1-nr5a2-mab-oti3h8-corafluor-1-25920251333441.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI3H8 |
| Applications: | IHC, WB |
Selective liver receptor homolog 1 (LRH1) inverse agonist
| Chemical Name: | 3-Cyclohexyl-6-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]-1H-pyrimidine-2,4-dione |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #PCRP-NR5A2-1B8 |
| Applications: | IHC, Flow |
![LRH-1/NR5A2 Antibody (PCRP-NR5A2-1B8) [mFluor Violet 610 SE]](https://resources.bio-techne.com/images/products/nbp3-26934mfv610_mouse-lrh-1-nr5a2-mab-pcrp-nr5a2-1b8-mfv610-762024922240.png "LRH-1/NR5A2 Antibody (PCRP-NR5A2-1B8) [mFluor Violet 610 SE]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #PCRP-NR5A2-1B8 |
| Applications: | IHC, Flow |
![LRH-1/NR5A2 Antibody (PCRP-NR5A2-1B8) [DyLight 350]](https://resources.bio-techne.com/images/products/nbp3-26934uv_mouse-lrh-1-nr5a2-mab-pcrp-nr5a2-1b8-dylight-350-7620249225363.jpg "LRH-1/NR5A2 Antibody (PCRP-NR5A2-1B8) [DyLight 350]")