LAT Products
LAT (Linker for Activation of T cells) is a type III transmembrane lipid raft protein that serves as a scaffold for signaling molecules. Upon T-cell antigen receptor activation, LAT is multiply phosphorylated by ZAP-70/Syk protein tyrosine kinases, creating docking sites for SH2 domain-containing proteins. For example, phospholipase C-gamma docks at Y161, which is pY132 in the short form. Mutation of this site results in a Th2 autoimmune lymphoproliferative disorder in mice.
115 results for "LAT" in Products
115 results for "LAT" in Products
LAT Products
LAT (Linker for Activation of T cells) is a type III transmembrane lipid raft protein that serves as a scaffold for signaling molecules. Upon T-cell antigen receptor activation, LAT is multiply phosphorylated by ZAP-70/Syk protein tyrosine kinases, creating docking sites for SH2 domain-containing proteins. For example, phospholipase C-gamma docks at Y161, which is pY132 in the short form. Mutation of this site results in a Th2 autoimmune lymphoproliferative disorder in mice.
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #LAT.10-17 |
| Applications: | IHC, WB, Flow, IP |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #627945 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #661002 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2E4 |
| Applications: | IHC, WB, ELISA, ICC/IF, IP |
| Reactivity: | Human, Mouse, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: LAT Antibody [NBP2-27104]](https://resources.bio-techne.com/images/products/LAT-Antibody-Western-Blot-NBP2-27104-img0001.jpg "Western Blot: LAT Antibody [NBP2-27104]")
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: LAT Antibody [NBP1-81324]](https://resources.bio-techne.com/images/products/LAT-Antibody-Western-Blot-NBP1-81324-img0006.jpg "Western Blot: LAT Antibody [NBP1-81324]")
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #627945 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #627945 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #627945 |
| Applications: | WB |