10 results for "Kir6.2 Small Molecules and Peptides" in Products
Kir6.2: Small Molecules and Peptides
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent ...
Kir6 blocker; non-hydrolyzable AMP analog
| Chemical Name: | Adenosine-5'-[(β,γ)-imido]triphosphate tetralithium salt |
| Purity: | ≥90% (HPLC) |
Kir6 (KATP) blocker; displays high affinity for SUR1/Kir6.2 channels
| Alternate Names: | A-4166,Senaglinide |
| Chemical Name: | N-[[4-(1-Methylethyl)cyclohexyl]carbonyl]-D-phenylalanine |
Kir6 (KATP) channel blocker
| Alternate Names: | Glyburide |
| Chemical Name: | 5-Chloro-N-[2-[4-[[[(Cylcohexylamino)carbonyl]amino]sulphonyl]phenyl]ethyl]-2-methoxybenzamide |
| Purity: | ≥98% (HPLC) |
Selective activator of SUR1 Kir6.2 channels
| Chemical Name: | 7-[[4-(1,1-Dimethylethyl)phenyl]methyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione |
| Purity: | ≥98% (HPLC) |
Kir6 (KATP) channel opener; active enantiomer of Cromakalim
| Alternate Names: | BRL 38227 |
| Chemical Name: | (3S,4R)-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile |
| Purity: | ≥98% (HPLC) |
Blocks IKr, hERG and L-type Ca2+ channels; class III antiarrhythmic
| Chemical Name: | (±)-N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]methanesulfonamide hemifumarate |
| Purity: | ≥98% (HPLC) |
Kir6 (KATP) channel blocker
| Alternate Names: | AG-EE 623ZW |
| Chemical Name: | 2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid |
| Purity: | ≥98% (HPLC) |
Kir6 channel (KATP) opener
| Chemical Name: | 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide |
| Purity: | ≥98% (HPLC) |
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker
| Chemical Name: | α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol |
| Purity: | ≥98% (HPLC) |
Antianginal, activates pyruvate dehydrogenase
| Alternate Names: | RS 43285 |
| Chemical Name: | N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
