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IL-27 Products

IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.

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187 results for "IL-27" in Products

187 results for "IL-27" in Products

IL-27 Products

IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.

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His-tag

Source: NS0
Accession #: Q14213.2 (EBI3) & AAM34498 (p28)
Applications: BA
R&D Systems Recombinant Proteins and Enzymes

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

The Mouse Cytokine Array, Panel A utilizes capture antibodies spotted onto a nitrocellulose membrane to allow high-throughput multi-analyte profiling of 40 cytokines, chemokines, and more in a single sample.
(3)

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

The Human XL Cytokine Array detects multiple cytokines, chemokines, growth factors and other soluble proteins in cell culture supernates.
(3)
Source: NS0
Accession #: O35228 (EBI3) & Q8K3I6 (p28)
Applications: BA
Recombinant Mouse IL-27 (NS0-expressed) Protein Bioactivity
(2)
Assay Range: 156 - 10,000 pg/mL
Applications: ELISA
Human IL-27 ELISA Standard Curve

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

(3)
Source: CHO
Accession #: XP_005587614.1 (EBI-3) & XP_028697194.1 (IL-27a)
Applications: BA
Recombinant Cynomolgus Monkey IL-27 His-tag Protein Bioactivity
(2)

Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.

Source: HEK293
Accession #: Q14213.2 & Q8NEV9.2
Applications: BA
(2)
Reactivity: Human, Mouse
Details: Rabbit IgG Polyclonal
Applications: WB, ICC/IF
Western Blot: IL-27 Antibody [NB100-56389]
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