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472 results for "IL-12" in Products

IL-12 Products

IL-12 (Interleukin-12) is a heterodimeric cytokine that consists of a p35 and a p40 subunit. p40 is also a subunit of the cytokine IL-23. IL-12 enhances the cytotoxic activity and induces IFN-gamma production in NK cells, T cells, and dendritic epidermal T cells, and it promotes a Th1 biased immune response. It signals through a receptor complex composed of IL-12 R beta 1 and IL-12 R beta 2. Both homodimeric p40, and IL-23 can bind to the IL-12 receptor, serving as non-signaling antagonists.

Reactivity:
Mouse
Assay Range:
7.8-500 pg/mL (Cell Culture Supernates, Serum)
Applications:
ELISA
Mouse IL-12 p70 ELISA Linearity
(2)

GS Linker, Defined heterodimer stoichiometry.

Reactivity:
Human
Source:
HEK293
Accession #:
P29460.1 (IL-12p40), P29459.2 (IL-12p35)
Applications:
Bioactivity
Recombinant Human IL-12 (linked heterodimer) Protein Bioactivity
(2)
Reactivity:
Mouse
Assay Range:
39.1-2500 pg/mL
Applications:
ELISA
Mouse IL-12 p70 ELISA Standard Curve
Reactivity:
Human
Assay Range:
31.2-2000 pg/mL
Applications:
ELISA
Human IL-12 p70 ELISA Standard Curve
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #24910
Applications:
IHC, WB, B/N
IL-12 p70 antibody in Human Kidney by Immunohistochemistry (IHC-P).
(2)
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, B/N, ICC/IF
Cell Proliferation Induced by IL‑12 and Neutralization by Human IL‑12 Antibody.
(4)
Reactivity:
Human, Mouse
Details:
Mouse IgG1 Monoclonal Clone #27537
Applications:
WB, Flow, CyTOF-ready
(3)
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
Cell Proliferation Induced by IL‑12 and Neutralization by Mouse IL‑12 Antibody.
Reactivity:
Porcine
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
Cell Proliferation Induced by IL‑12 and Neutralization by Porcine IL‑12 Antibody.
Reactivity:
Mouse
Details:
Rat IgG1 Monoclonal Clone #48110
Applications:
WB, ELISA(Cap)
Reactivity:
Mouse
Source:
Sf 21 (baculovirus)
Accession #:
P43432 (p40) & NP_032377 (p35)
Applications:
Bioactivity
Recombinant Mouse IL-12 Protein Bioactivity
(2)
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, ELISA, B/N, ICC/IF
Immunohistochemistry: IL-12 Antibody [NB600-1443]
(8)
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA(Det), ICC/IF
IL-12 antibody in Human PBMCs by Immunocytochemistry (ICC).
(3)
Reactivity:
Feline
Source:
Sf 21 (baculovirus)
Accession #:
O02744 (p40) & O02743 (p35)
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Canine
Source:
CHO
Accession #:
Q28268 (p40) & Q28267 (p35)
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Porcine
Source:
CHO
Accession #:
Q28938 (p40) & Q29053 (p35)
Applications:
Bioactivity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
Cell Proliferation Induced by IL‑12 and Neutralization by Human IL‑12 Antibody.
Reactivity:
Mouse
Details:
Rat IgG2A Monoclonal Clone #45806
Applications:
IHC
IL-12/IL-35 p35 antibody in Mouse Spleen by Immunohistochemistry (IHC-Fr).

Recombinant Monoclonal Antibody.

Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #24945R
Applications:
ELISA(Cap), ICC/IF
(2)
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA(Det)
Reactivity:
Human, Mouse
Details:
Mouse IgG1 Monoclonal Clone #27537
Applications:
Flow
(2)
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
Cell Proliferation Induced by IL‑12 and Neutralization by Mouse IL‑12 Antibody.
Reactivity:
Mouse
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
Cell Proliferation Induced by IL‑12 and Neutralization by Mouse IL‑12 Antibody.
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