IL-12/IL-23 p40: Proteins and Enzymes
IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.
Products:
7 results for "IL-12/IL-23 p40 Proteins and Enzymes" in Products
7 results for "IL-12/IL-23 p40 Proteins and Enzymes" in Products
IL-12/IL-23 p40: Proteins and Enzymes
IL-12 (Interleukin-12) is a secreted heterodimeric cytokine that contains disulfide-linked p35 and p40 subunits. The p40 subunit is also a subunit of the heterodimeric IL-23. IL-12 is produced by macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, keratinocytes, microglia, and non-germinal center B cells. It acts through a receptor complex that contains the ligand binding IL-12 R alpha 1 and the signal transducing IL-12 R alpha 2. IL-12 can enhance cytotoxic activity and induce Interferon-gamma production in NK cells, T cells, and dendritic epidermal T cells. In conjunction with IL-23 and IL-27, IL-12 promotes the development of a Th1 immune response.
Products:
| Source: | Sf 21 (baculovirus) |
| Accession #: | P29460 |
| Applications: | BA |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P43432.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P43432 |
| Applications: | BA |
| Source: | HEK293 |
| Accession #: | P29460.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | O02744 |
| Applications: | Bind |
| Source: | NS0 |
| Accession #: | Q28268 |
| Applications: | Bind |
| Source: | NS0 |
| Accession #: | P43432, Q8K3I6 |
| Applications: | BA |
