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5 results for "IL-1 beta/IL-1F2 Small Molecules and Peptides" in Products

IL-1 beta/IL-1F2 Small Molecules and Peptides

IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal ...

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Potent, selective human type I IL-1 receptor antagonist

Purity:
≥95%
Potent, selective human type I IL-1 receptor antagonist

Active metabolite binds CPSF3; Pro-drug

Alternate Names:
TO-207
Chemical Name:
N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride
Purity:
≥98%
Active metabolite binds CPSF3; Pro-drug

Selective inhibitor of c-Fos/activator protein (AP)-1

Chemical Name:
5-[4-(Cyclopentyloxy)-2-hydroxybenzoyl]-2-[(2,3-dihydro-3-oxo-1,2-benzisoxazol-6-yl)methoxy]benzenepropanoic acid
Purity:
≥98%
Selective inhibitor of c-Fos/activator protein (AP)-1

Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

Chemical Name:
4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
Purity:
≥98%
Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

Selective inhibitor of c-Fos/activator protein (AP)-1

Chemical Name:
5-[4-(Cyclopentyloxy)-2-hydroxybenzoyl]-2-[(2,3-dihydro-3-oxo-1,2-benzisoxazol-6-yl)methoxy]benzenepropanoic acid
Purity:
≥98%
Selective inhibitor of c-Fos/activator protein (AP)-1
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