Flt-3/Flk-2 Products
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.
376 results for "Flt-3/Flk-2" in Products
376 results for "Flt-3/Flk-2" in Products
Flt-3/Flk-2 Products
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and STK-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes c-kit, the receptor for SCF, and fms, the receptor for M-CSF. Mouse Flt-3 shares 85% amino acid sequence identity with human Flt-3. Flt-3 expression has been detected in various tissues, including placenta, gonads, and tissues of nervous and hematopoietic origin.
Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies
Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
| Alternate Names: | Semaxinib |
| Chemical Name: | 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one |
| Purity: | ≥98% (HPLC) |
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
| Alternate Names: | CEP-701 |
| Chemical Name: | (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #66903 |
| Applications: | Flow, CyTOF-ready |
Highly potent FLT3 inhibitor
| Chemical Name: | N-[5-(1,1-Dimethylethyl)-3-isoxazolyl]-N'-[4-[7-[2-(4-morpholinyl)ethoxy]imidazo[2,1-b]benzothiazol-2-yl]phenyl]urea |
| Purity: | ≥98% (HPLC) |
Potent FLT3 inhibitor
| Chemical Name: | 2-[(3,4-Dimethoxybenzoyl)amino]-4,5,6,7-benzo[b]thiophene-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
| Alternate Names: | LDK378 |
| Chemical Name: | 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine |
| Purity: | ≥98% (HPLC) |
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
| Chemical Name: | 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready |
Potent FLT3 inhibitor; also potently inhibits AXL
| Chemical Name: | 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R
| Chemical Name: | N-[4-(3-Amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #113308 |
| Applications: | Flow, CyTOF-ready, ICC |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA, Flow, CyTOF-ready |
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
| Chemical Name: | 4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective PDGFR family inhibitor
| Chemical Name: | N-[4-[[[[5-(1,1-Dimethethylethyl)-3-isoxazolyl]amino]carbonyl]amino]phenyl]-5-[(1-ethyl-2,2,6,6-tetramethyl-4-piperidinyl)oxy]-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
| Source: | NS0 |
| Accession #: | AAA18947 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western, ICC |
| Source: | HEK293 |
| Accession #: | P36888 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Lambda Monoclonal Clone #7E8.2C8 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready |
![Western Blot: Flt-3/Flk-2/CD135 Antibody (7E8.2C8)Azide and BSA Free [NBP2-80739]](https://resources.bio-techne.com/images/products/Flt-3-Flk-2-CD135-Antibody-7E8-2C8-Azide-and-BSA-Free-Western-Blot-NBP2-80739-img0001.jpg "Western Blot: Flt-3/Flk-2/CD135 Antibody (7E8.2C8)Azide and BSA Free [NBP2-80739]")
| Source: | NS0 |
| Accession #: | Q00342 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #113308 |
| Applications: | Flow |
Potent VEGFR, PDGFRβ and KIT inhibitor
| Alternate Names: | SU 11248 |
| Chemical Name: | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
| Purity: | ≥98% (HPLC) |
