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6 results for "ErbB4/Her4" in Products
ErbB4/Her4 Products
ErbB4, also known as Her4, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the EGF family of growth factors. ErbB4 ligands include the neuregulins, betacellulin and heparin-binding EGF-like growth factor (HB-EGF).
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
Alternate Names:
Tyrphostin AG 490
Chemical Name:
(E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide
Purity:
≥98%
Negative control for PP 2 (Cat. No. 1407)
Chemical Name:
1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity:
≥98%
Potent ErbB receptor family inhibitor
Chemical Name:
N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine
Purity:
≥98%
Potent EGFR and VEGFR inhibitor
Chemical Name:
6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Purity:
≥98%
Potent irreversible pan ErbB inhibitor
Alternate Names:
PF00299804
Chemical Name:
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide
Purity:
≥98%
Potent dual specificity EGFR/HER2 inhibitor; active in vivo
Alternate Names:
BIBW2992
Chemical Name:
(2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide dimaleate
Purity:
≥98%
