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3 results for "COMT Small Molecules and Peptides" in Products

COMT: Small Molecules and Peptides

COMT (Catechol-O-MethylTransferase) is a 29-30 kDa member of the COMT family of enzymes. It shares the same acronym with plant COMT, or caffeic acid 3-O-methyltransferase that is involved in phenylpropanoid synthesis. Mammalian COMT is widely expressed, and catalyzes the O-methylation of catecholamines, dopamine and estrogen. Human COMT is a 271 amino acid (aa) type II transmembrane (TM) protein. It contains a six aa cytoplasmic N-terminus, an 20 aa TM segment, and a 245 aa ...

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COMT inhibitor

Potent COMT inhibitor; blocks α-synuclein aggregation

COMT inhibitor; also inhibits transthyretin aggregation

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