4 results for "Catechol O-Methyltransferase (COMT) Inhibitors" in Products
Catechol O-Methyltransferase (COMT) Inhibitors Products
Catechol O-Methyltransferase (COMT) (EC 2.1.1.6) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to a catechol substrate in the presence of magnesium (Mg2+) ions. COMT substrates include dopamine, norepinephrine, epinephrine and levodopa. There are two isoforms of COMT: soluble (S-) COMT and membrane-bound (MB-) COMT.
COMT is ubiquitously expressed, with the highest COMT activity occurring in the liver and kidneys. Notable expression of COMT occurs in kidney ...
COMT inhibitor
| Chemical Name: | 3,5-Dinitrocatechol |
| Purity: | ≥99% (HPLC) |
COMT inhibitor
| Chemical Name: | 5-[3-(2,5-Dichloro-4,6-dimethyl-1-oxido-3-pyridinyl)-1,2,4-oxadiazol-5-yl]-3-nitro-1,2-benzenediol |
| Purity: | ≥98% (HPLC) |
COMT inhibitor; also inhibits transthyretin aggregation
| Alternate Names: | Tasmar,Ro 40-7592 |
| Chemical Name: | (3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone |
| Purity: | ≥98% (HPLC) |
Potent COMT inhibitor; blocks α-synuclein aggregation
| Chemical Name: | (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide |
| Purity: | ≥98% (HPLC) |
