Caspase-3 Products
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.
Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.
Products:
226 results for "Caspase-3" in Products
226 results for "Caspase-3" in Products
Caspase-3 Products
Caspase-3 is a widely expressed dimeric peptidase that is the major executioner caspase, the primary downstream mediator of apoptotic-associated proteolysis. Caspase-3 cleaves multiple substrates including PARP, proIL-16, PKC-gamma and -delta, proCaspases-6, -7, and -9, and beta-Catenin.
Normally, it is an inactive, exclusively cytosolic homodimer. During apoptosis, however, proCaspase-3 is activated by cleavage into p20 and p12 subunits, and the p20 subunit is trimmed to yield a p17 subunit. Active Caspase-3 contains two p17 and two p12 subunits.
Products:
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC |
| Reactivity: | Human, Mouse, Rat, Porcine, Rabbit, +5 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #31A1067 |
| Applications: | IHC, WB, ICC/IF, Flow, CyTOF-ready, +5 More |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #269518 |
| Applications: | WB, IHC, ICC, ICFlow |
| Reactivity: | Human, Mouse, Rat, Gerbil |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, IP |
![Immunohistochemistry: Caspase-3 Antibody - (active/cleaved) [NB100-56113]](https://resources.bio-techne.com/images/products/Caspase-3-Antibody-active-cleaved-Immunohistochemistry-NB100-56113-img0005.jpg "Immunohistochemistry: Caspase-3 Antibody - (active/cleaved) [NB100-56113]")
| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +4 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: Caspase-3 Antibody [NB600-1235]](https://resources.bio-techne.com/images/products/Caspase-3-Antibody-Immunohistochemistry-Paraffin-NB600-1235-img0003.jpg "Immunohistochemistry-Paraffin: Caspase-3 Antibody [NB600-1235]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #CPP32 4-1-18 |
| Applications: | IHC, WB, ICC/IF, IP, Simple Western |
![Western Blot: Caspase-3 Antibody (CPP32 4-1-18)BSA Free [NB500-210]](https://resources.bio-techne.com/images/products/Caspase-3-Antibody-CPP32-4-1-18-Western-Blot-NB500-210-img0008.jpg "Western Blot: Caspase-3 Antibody (CPP32 4-1-18)BSA Free [NB500-210]")
| Source: | E. coli |
| Accession #: | P42574 |
| Applications: | EnzAct |
| Assay Range: | 219 - 14,000 pg/mL |
| Applications: | ELISA |
Contains 4 membranes - each spotted in duplicate with 35 different apoptosis antibodies
| Reactivity: | Human, Mouse, Rat, Canine, Gerbil |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP, ChIP, Simple Western |
![Western Blot: Caspase-3 Antibody(Pro and Active) [NB100-56112]](https://resources.bio-techne.com/images/products/Caspase-3-Antibody-Pro-and-Active-Western-Blot-NB100-56112-img0010.jpg "Western Blot: Caspase-3 Antibody(Pro and Active) [NB100-56112]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IP, KO |
Potent pro-apoptotic anticancer agent; activates caspase-3
| Alternate Names: | CDDP |
| Chemical Name: | cis-Diaminodichloroplatinum |
| Reactivity: | Human |
| Details: | Mouse IgG Monoclonal Clone #31A893 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Caspase-3 Antibody (31A893)BSA Free [NB100-56709]](https://resources.bio-techne.com/images/products/Caspase-3-Antibody-31A893-Western-Blot-NB100-56709-img0009.jpg "Western Blot: Caspase-3 Antibody (31A893)BSA Free [NB100-56709]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #269518 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #269518 |
| Applications: | ICFlow |
| Source: | E. coli |
| Accession #: | AAA65015 |
| Applications: | EnzAct |
Contains 8 membranes - each spotted in duplicate with 21 different apoptosis antibodies
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #84803 |
| Applications: | WB, KO |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #269518 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1112I |
| Applications: | Dual ISH-IHC, ICC |
| Applications: | ELISA |
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Caspase-3 Antibody [NBP1-90125]](https://resources.bio-techne.com/images/products/Caspase-3-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-90125-img0015.jpg "Immunocytochemistry/ Immunofluorescence: Caspase-3 Antibody [NBP1-90125]")
Selective cyclooxygenase-2 (COX-2) inhibitor
| Alternate Names: | SC 58635,Celebrex |
| Chemical Name: | 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #269518 |
| Applications: | ICFlow |
