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Bax-alpha Products

B cell leukemia/lymphoma-2 associated X protein (Bax) is a pro-apoptotic member of the Bcl-2 family of proteins found in many cell types. Bax is a cytosolic protein that translocates to the mitochondria and participates in Cytochrome c release in response to apoptotic stimuli. Aberrant expression of Bcl-2 family members can inappropriately promote or prevent apoptosis. Increased expression of Bax is associated with the apoptotic loss of neurons in Parkinson's disease.

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4 results for "Bax-alpha" in Products

4 results for "Bax-alpha" in Products

Bax-alpha Products

B cell leukemia/lymphoma-2 associated X protein (Bax) is a pro-apoptotic member of the Bcl-2 family of proteins found in many cell types. Bax is a cytosolic protein that translocates to the mitochondria and participates in Cytochrome c release in response to apoptotic stimuli. Aberrant expression of Bcl-2 family members can inappropriately promote or prevent apoptosis. Increased expression of Bax is associated with the apoptotic loss of neurons in Parkinson's disease.

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Assay Range: 312 - 20,000 pg/mL
Applications: ELISA

Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines

Chemical Name: 4-[4-[(4'-Chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]benzamide
Purity: ≥98% (HPLC)
Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines

High affinity and selective activator of Bax

Chemical Name: 2-[(2-Nitro-9H-fluorene-9-ylidene)methyl]phenol
Purity: ≥98% (HPLC)
High affinity and selective activator of Bax

Allosteric inhibitor of Bax channel activation

Alternate Names: BAI1
Chemical Name: 3,6-Dibromo-α-(1-piperazinylmethyl)-9H-carbazole-9-ethanol dihydrochloride
Purity: ≥98% (HPLC)
Allosteric inhibitor of Bax channel activation
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