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242 results for "BACE-1" in Products

BACE-1 Products

Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.

BACE1 and BACE2 inhibitor

Chemical Name: N-[3-[(5R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide
Purity: ≥98% (HPLC)
BACE1 and BACE2 inhibitor
Source: NS0
Accession #: P56817.1
Applications: EnzAct
R&D Systems Recombinant Proteins and Enzymes

Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies

R&D Systems Proteome Profiler Antibody Array Kits

Potent and selective β-secretase (BACE) inhibitor

Chemical Name: N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride
Purity: ≥98% (HPLC)
Potent and selective β-secretase (BACE) inhibitor
Reactivity: Human, Mouse
Details: Mouse IgG1 Monoclonal Clone #137612
Applications: ELISA
Rat BACE-1 ELISA Kit (Colorimetric)
(2)

Recombinant Monoclonal Antibody

Reactivity: Mouse, Rat
Details: Rabbit IgG Monoclonal Clone #S03-9C8
Applications: WB
Western Blot: BACE-1 Antibody (S03-9C8) [NBP3-19577]
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