BACE-1 Products
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
205 results for "BACE-1" in Products
205 results for "BACE-1" in Products
BACE-1 Products
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137612 |
| Applications: | WB, IHC, CyTOF-ready, ICFlow |
| Source: | NS0 |
| Accession #: | P56817.1 |
| Applications: | EnzAct |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137626 |
| Applications: | IP, Neut |
BACE1 and BACE2 inhibitor
| Chemical Name: | N-[3-[(5R)-3-Amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #3C1C3 |
| Applications: | WB, ELISA, ICC/IF, Flow, CyTOF-ready |
![Western Blot: BACE-1 Antibody (3C1C3)BSA Free [NBP2-37261]](https://resources.bio-techne.com/images/products/BACE-1-Antibody-3C1C3-Western-Blot-NBP2-37261-img0004.jpg "Western Blot: BACE-1 Antibody (3C1C3)BSA Free [NBP2-37261]")
Potent and selective β-secretase (BACE) inhibitor
| Chemical Name: | N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
| Source: | NS0 |
| Accession #: | P56818 |
| Applications: | EnzAct |
| Assay Range: | 0.625 - 40 ng/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137612 |
| Applications: | ICFlow |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #2C1 |
| Applications: | IHC, WB, ELISA, Func |
![Western Blot: BACE-1 Antibody (2C1) [H00023621-M01]](https://resources.bio-techne.com/images/products/BACE-1-Antibody-2C1-Western-Blot-H00023621-M01-img0005.jpg "Western Blot: BACE-1 Antibody (2C1) [H00023621-M01]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137626 |
| Applications: | IP, Neut |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137626 |
| Applications: | IP, Neut |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137612 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137612 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137612 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137612 |
| Applications: | ICFlow |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137612 |
| Applications: | ICFlow |
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: BACE-1 Antibody [NBP3-13390]](https://resources.bio-techne.com/images/products/BACE-1-Antibody-Western-Blot-NBP3-13390-img0001.jpg "Western Blot: BACE-1 Antibody [NBP3-13390]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137626 |
| Applications: | IP, Neut |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137626 |
| Applications: | IP, Neut |