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2 results for "BACE-1 Small Molecules and Peptides" in Products
BACE-1 Small Molecules and Peptides
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
Potent and selective β-secretase (BACE) inhibitor
Chemical Name:
N-[3-[(4aS,7aS)-2-Amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl]-5-fluoro-2-pyridinecarboxamide hydrochloride
Purity:
≥98%
Cell-permeable fluorescent amyloid stain. Used for: in vitro Aβ staining in brain tissues.
Chemical Name:
2-[4-(Dimethylamino)phenyl]-3,6-dimethylbenzothiazolium chloride
Purity:
≥95%
