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3 results for "BACE-1 Proteins and Enzymes" in Products

BACE-1 Proteins and Enzymes

Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.

Reactivity:
Human
Source:
NS0
Accession #:
P56817.1
Applications:
Enzyme Activity
Reactivity:
Mouse
Source:
NS0
Accession #:
P56818
Applications:
Enzyme Activity
R&D Systems Recombinant Proteins and Enzymes
Reactivity:
Mouse
Source:
NS0
Accession #:
P56818
Applications:
Enzyme Activity
R&D Systems Recombinant Proteins and Enzymes
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