Aurora A: Small Molecules and Peptides
The mammalian Aurora kinase family contains three serine/threonine kinase members that participate in cell division. They impact cytokinesis and chromatid segregation during the G2/M phase of cell division. Aurora A influences centrosome maturation and spindle assembly, while Auroras B and C direct chromosome alignment and segregation.
3 results for "Aurora A Small Molecules and Peptides" in Products
3 results for "Aurora A Small Molecules and Peptides" in Products
Aurora A: Small Molecules and Peptides
The mammalian Aurora kinase family contains three serine/threonine kinase members that participate in cell division. They impact cytokinesis and chromatid segregation during the G2/M phase of cell division. Aurora A influences centrosome maturation and spindle assembly, while Auroras B and C direct chromosome alignment and segregation.
Aurora A Degrader (PROTAC®)
| Chemical Name: | trans-4-(3-Chloro-2-fluorophenoxy)-N-(2-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)ethoxy)ethoxy)ethyl)-1-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)cyclohexane-1-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent pan-Aurora kinase inhibitor
| Chemical Name: | N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine |
| Purity: | ≥98% (HPLC) |
Potent, selective Aurora kinase A inhibitor
| Chemical Name: | 2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile hydrochloride |
| Purity: | ≥98% (HPLC) |
