ALOX12B Products

ALOX12B, or Arachidonate 12-lipoxygenase, 12R-type has a 701 amino acid isoform that is 80 kDa, and is involved in the transformation of arachidonic acid into 12R-hydroxyeicosatetraenoic acid. Current research is being studied on the relation between ALOX12B and a variety of diseases and disorders including epithelial ovarian cancer, meningioma, breast cancer, leukemia, tonsillitis, ichthyosis, anhidrosis, autosomal recessive congenital ichthyosis, and dermatitis. This protein interacts with LMNA, KRT5, ALOX12, ALOX15, and ALOX15B in arachidonic acid metabolism, 112-eicosatetraenoic acid derivative synthesis, and lipid and lipoprotein metabolism.