7 results for "AHR Small Molecules and Peptides" in Products
AHR: Small Molecules and Peptides
AHR (Aryl-hydrocarbon receptor; also bHLHE76) is a 110 kDa member of the bHLH/PAS transcription factor family. It is widely expressed (breast, lung, liver), and serves many functions. First, it binds multiple xenobiotic chemicals in the cytoplasm. This induces dimerization with ARNT, translocation to the nucleus, and activation of P450 genes such as CYP1A1 and UGT1A6. Second, it appears to block cell cycle progression, possibly via a down-regulation of CDK proteins. And third, it blocks ...
Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment
| Chemical Name: | 4-[2-[[2-Benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]phenol |
| Purity: | ≥98% (HPLC) |
Potent aryl hydrocarbon receptor (AhR) antagonist
| Chemical Name: | 1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide |
| Purity: | ≥98% (HPLC) |
High affinity aryl hydrocarbon receptor (AhR) agonist
| Chemical Name: | 5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehyde |
| Purity: | ≥95% (HPLC) |
Potent aryl hydrocarbon receptor (AhR) agonist; orally bioavailable
| Chemical Name: | 10-Chloro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one |
| Purity: | ≥97% (HPLC) |
p53 inhibitor. Also aryl hydrocarbon receptor agonist
| Chemical Name: | 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide |
Endogenous agonist for the transcription factor aryl hydrocarbon receptor
| Alternate Names: | Aryl hydrocarbon receptor ligand |
| Chemical Name: | 2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylic acid methyl ester |
| Purity: | ≥98% (HPLC) |
Prodrug of the antitumor agent 5F 203
| Chemical Name: | (2S)-2,6-Diamino-N-[4-(5-fluoro-2-benzothiazolyl)-2-methylphenyl]hexanamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
