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7 results for "Abl Kinase Inhibitors" in Products
Abl Kinase Inhibitors
Highly potent pan-Src/Bcr-Abl inhibitor
Alternate Names:
BMS-354825
Chemical Name:
N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide
Purity:
≥98%
Dual Src-Abl inhibitor; antiproliferative
Alternate Names:
SKI-606
Chemical Name:
4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile
Purity:
≥98%
Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
Alternate Names:
Gleevec,CGP 57148B
Chemical Name:
4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
Purity:
≥98%
Src family kinase inhibitor; also inhibits c-Abl
Alternate Names:
1-NA-PP 1
Chemical Name:
1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity:
≥98%
Potent multi-kinase and pan-Bcr-Abl inhibitor
Alternate Names:
Ponatinib
Chemical Name:
3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-benzamide
Purity:
≥98%
Potent inhibitor of Abl T315l mutant and wild-type Abl kinases
Chemical Name:
5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethyl-3-pyridinecarboxamide
Purity:
≥98%
Selective allosteric inhibitor of Bcr-Abl; analog of GNF 2 (Cat. No. 4399)
Chemical Name:
N-(2-Hydroxyethyl)-3-[6-[[4-(trifluoromethoxy)phenyl]amino]-4-pyrimidinyl]benzamide
Purity:
≥98%
