15-PGDH/HPGD Products
HPGD, or 15-hydroxyprostaglandin dehydrogenase, is a NAD+-linked dehydrogenase that oxidizes the hydroxyl group at position 15 of prostaglandins to a ketone, resulting in a loss of biological activity. HPGD is a major enzyme for the catabolism of prostaglandins. The enzyme is a member of the short-chain alcohol dehydrogenase family of enzymes. HPGD is a cytosolic enzyme expressed in most tissues, with highest expression levels in placenta, lung, and kidney. It is inhibited by aspirin and nonsteroidal anti-inflammatory drugs. Defects in HPGD are a cause of hypertrophic osteoarthropathy.
75 results for "15-PGDH/HPGD" in Products
75 results for "15-PGDH/HPGD" in Products
15-PGDH/HPGD Products
HPGD, or 15-hydroxyprostaglandin dehydrogenase, is a NAD+-linked dehydrogenase that oxidizes the hydroxyl group at position 15 of prostaglandins to a ketone, resulting in a loss of biological activity. HPGD is a major enzyme for the catabolism of prostaglandins. The enzyme is a member of the short-chain alcohol dehydrogenase family of enzymes. HPGD is a cytosolic enzyme expressed in most tissues, with highest expression levels in placenta, lung, and kidney. It is inhibited by aspirin and nonsteroidal anti-inflammatory drugs. Defects in HPGD are a cause of hypertrophic osteoarthropathy.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KD, Simple Western |
![Simple Western: 15-PGDH/HPGD Antibody [NB200-179]](https://resources.bio-techne.com/images/products/15-PGDH-HPGD-Antibody-Simple-Western-NB200-179-img0005.jpg "Simple Western: 15-PGDH/HPGD Antibody [NB200-179]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western |
| Source: | E. coli |
| Accession #: | P15428 |
| Applications: | EnzAct |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: 15-PGDH/HPGD Antibody [NBP1-87061]](https://resources.bio-techne.com/images/products/15-PGDH-HPGD-Antibody-Western-Blot-NBP1-87061-img0022.jpg "Western Blot: 15-PGDH/HPGD Antibody [NBP1-87061]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2C10 |
| Applications: | IHC, WB, Flow |
![Western Blot: 15-PGDH/HPGD Antibody (OTI2C10) [NBP2-00490]](https://resources.bio-techne.com/images/products/15-PGDH-Antibody-2C10-Western-Blot-NBP2-00490-img0004.jpg "Western Blot: 15-PGDH/HPGD Antibody (OTI2C10) [NBP2-00490]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ELISA |
![Western Blot: 15-PGDH/HPGD Antibody [NB100-1482]](https://resources.bio-techne.com/images/products/15-PGDH-HPGD-Antibody-Western-Blot-NB100-1482-img0006.jpg "Western Blot: 15-PGDH/HPGD Antibody [NB100-1482]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: 15-PGDH/HPGD Antibody [NBP2-21588]](https://resources.bio-techne.com/images/products/15-PGDH-Antibody-Western-Blot-NBP2-21588-img0001.jpg "Western Blot: 15-PGDH/HPGD Antibody [NBP2-21588]")
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | WB, IP |
![Western Blot: 15-PGDH/HPGD Antibody (101) [NBP2-90625]](https://resources.bio-techne.com/images/products/15-PGDH-HPGD-Antibody-101-Western-Blot-NBP2-90625-img0003.jpg "Western Blot: 15-PGDH/HPGD Antibody (101) [NBP2-90625]")
| Applications: | WB |
![Western Blot: 15-PGDH/HPGD Overexpression Lysate [NBL1-11693]](https://resources.bio-techne.com/images/products/15-PGDH-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11693-img0002.jpg "Western Blot: 15-PGDH/HPGD Overexpression Lysate [NBL1-11693]")
| Applications: | ELISA |
![ELISA: Human 15-PGDH/HPGD ELISA Kit (Colorimetric) [NBP2-80340]](https://resources.bio-techne.com/images/products/Human-15-PGDH-HPGD-ELISA-Kit-Colorimetric-ELISA-NBP2-80340-img0001.jpg "ELISA: Human 15-PGDH/HPGD ELISA Kit (Colorimetric) [NBP2-80340]")
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
![Western Blot: 15-PGDH/HPGD Antibody [NBP2-98291]](https://resources.bio-techne.com/images/products/15-PGDH-HPGD-Antibody-Western-Blot-NBP2-98291-img0003.jpg "Western Blot: 15-PGDH/HPGD Antibody [NBP2-98291]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #016 |
| Applications: | ICC/IF, Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | WB, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | WB, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #004 |
| Applications: | ELISA |
High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
| Chemical Name: | 2-(Butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridin-3-amine |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | WB, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | WB, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #027 |
| Applications: | ICC/IF, Flow |
![15-PGDH/HPGD Antibody (027) [Alexa Fluor® 350]](https://resources.bio-techne.com/images/products/nbp2-89841af350_rabbit-monoclonal-15-pgdh-hpgd-antibody-027-alexa-fluor-350-288202315334013.jpg "15-PGDH/HPGD Antibody (027) [Alexa Fluor® 350] [NBP2-89841AF350] -")