Webinar: Clonality is King: Advancing Cell Line Development with Automated Single Cell Dispensing

Single cell isolation is a necessary step for a variety of applications from developing productive, stable cell lines for biologics manufacturing to developing CRISPR-edited iPSCs for disease modeling and pharmaceutical development. Traditionally, manual approaches (i.e., limited dilution) or FACS have been used to isolate single cells to generate clonal cell lines. However, these approaches have high labor demand and low yield and can increase development timelines. The Pala™ Cell Sorting and Single Cell Dispenser from Bio-Techne automates single cell isolation with dual laser fluorescence and gentle cell dispensing that can improve hit quantity and quality, saving time and yielding better outcomes. 

Speaker: 

Ryan McComb, Ph.D. 
Product Manager, Cellular Analysis; Bio-Techne 

Ryan McComb is the Product Manager for the Bio-techne Pala Cell Sorter and Single Cell Dispensing technology. He holds a B.S. in Cell Biology from the University of California, San Diego and a Masters of Business & Science and a Ph.D. from Keck Graduate Institute (Claremont, CA). He completed a post-doc at Stanford University in the Department of Genetics studying nucleotide repeat expansion diseases. Prior to joining Bio-Techne, Ryan worked as a Scientist and Product Manager at Recursion Pharmaceuticals. Ryan’s experience in both academia and industry has included leading diverse projects including small molecule pharmaceutical development for cardiac and neurodegenerative disease, high-throughput NGS approaches for AI drug discovery, and vaccine development using plant-based and mammalian-based manufacturing technologies.