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Testimonials and Interviews from your Peers

Read testimonials and interviews from your peers, to find out how scientists like you are driving pioneering research and diagnostics forward using Bio-Techne reagents, kits and instruments.

Our testimonials cover a range of research areas and applications, using everything from gold standard to GMP reagents, and revolutionary, award-winning instruments.

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  • RNAscope™ Spotlights

    What our customers are saying:

  • Unlocking the power of organoids in personalized medicine

    It is key technologies like RNAscope used after scRNAseq that is enabling us to visualize the genes in the context of the whole tissue...and pave the way for therapeutic approaches to intestinal diseases.

  • Harnessing spatial biology to uncover the cellular landscape of colorectal cancer

    Being able to spatially resolve cells in tissue using tools like RNAscope™ …will have a lot of clinical relevance in the future… that’s where the real power of this can be seen going from bench to bedside.

  • Shedding Light on Human Cerebral Cortical Folding and Channelopathies

    The RNAscope assay was very helpful in discovering this, not only because we were able to confidently discern between the different sodium channels, but also because we could use the RNAscope Multiplex Fluorescent kit v2 in situ assay to co-localize gene expression with cell types.

  • Insights into viral pathogenesis: Determination of causation by highly sensitive and specific viral RNA detection and localization with RNAscope ISH

    With its importance in understanding causality and the viral-host relationship, RNAscope technology has been a vital tool in my research... a method as sensitive as RNAscope assay with spatial resolution is absolutely irreplaceable for our confidence in determining viral contribution to a disease.

  • Detecting a Novel Circovirus in Foxes with Meningoencephalitis: How custom RNAscope™ assay probes are enhancing viral understanding

    In fact, we would certainly recommend RNAscope technology to researchers wanting to examine a target of interest for which there is not a reliable antibody available

  • Exploring GPCR expression in the eye: From discovery with NGS to spatial and quantitative expression confirmation with RNAscope™ technology

    Because RNAscope can detect expression of multiple genes in parallel, it can tell us whether those genes discovered through RT-PCR are co-expressed in the same cell or not – information that is very valuable and hard to obtain by other means.

  • Development of Prostate Cancer Personalized Medicine: Advancing analysis of prostate tumor molecular heterogeneity by combined immunohistochemistry and novel RNA in situ hybridization

    The development of combined protein and RNA detection methods may alleviate many concerns for accurate detection of biomarkers, and I can see this being the standard practice in future molecular cancer profiling... Given the unique probe design and detection chemistry of the RNAscope method, we were able to get results with high specificity and sensitivity for many probes that we have used in my laboratory. To date we don’t have any comparable technology for the reliable detection of RNA in FFPE tissues other than RNAscope.

  • Realizing the potential of long noncoding RNA as a cancer biomarker: From NGS discovery to validation with RNA in situ Hybridization

    The routine detection of non-coding RNA presents a particular set of challenges since they do not have protein counterparts for antibody detection. This is why the ability to detect RNA in cancer biopsy samples is so valuable, opening up the use of lncRNA as a biomarker.

  • Characterizing LGR5 stem cells in colorectal adenomas and carcinomas: Overcoming the limitations of antibody-based detection methods

    Using the RNAscope assay probe against LGR5 mRNA has allowed us to study the localization of LGR5 expression without relying on an antibody. I would certainly recommend RNAscope technology to researchers wanting to examine a target of interest for which there is not a reliable antibody available.

  • Tatiana Moves Closer to Treating Neurodegenerative Diseases With Jess

    Simple Western

    Jess is faster and more reliable in terms of quantification and allows us to use low sample volumes, for example, difficult-to-obtain samples such as iPSC-derived neurons.

  • From a Postdoc’s Perspective: Sarah Hopp

    I've enjoyed teaching and mentoring more than I ever expected, and knowing that about myself has allowed me to pursue a specific career track as I apply for faculty positions that strongly emphasize undergraduate education.