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Spear UltraDetect™ Assay Resources

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Application Notes & Technical Notes

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Successive Proximity Extension Amplification Reaction (SPEAR) and its Two-Factor Authentication Mechanism

Discover how this ultrasensitive immunoassay platform detects blood-based protein biomarkers of Alzheimer’s disease at fg/mL levels, enabling early prognosis, screening, and therapy monitoring.

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Unlocking the Potential of pTau 231 in Alzheimer’s Disease Research with the Enhanced Sensitivity and Precision of the SPEAR UltraDetect™ pTau 231 Assay

See how the SPEAR UltraDetect™ pTau 231 Assay sets a new benchmark for one of the most promising plasma biomarkers for early Alzheimer’s detection.

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Unparalleled Precision of SPEAR UltraDetect™ Immunoassays with Homogeneous Format: GFAP and NF-L

Discover how SPEAR UltraDetect™ NF-L and GFAP Assays can reveal neurological biomarker insights that other assays miss.

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SPEAR UltraDetect™ Neurofilament Light Exceptional Precision with F.A.S.T.™ Automated Workflow

Explore how SPEAR technology delivers superior sensitivity and specificity in detecting Neurofilament Light (NF-L) compared to conventional immunoassays, enabling ultra-sensitive protein detection from sub-microliter serum or plasma samples.

Posters

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SPEAR UltraDetect Immunoassays Demonstrating Consistent Biomarker Quantificiation Across Diverse qPCR Platforms and Laboratories

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SPEAR UltraDetect™ pTau 217: A High-Accuracy Scalable Plasma Biomarker for PET Confirmed Cognitively Impaired Patients Using a Single Cutoff