TP 238

Name: TP 238
Brand: Tocris Bioscience
SKU: 6670

Tocris Bioscience, part of Bio-Techne | Catalog # 6670

COA / SDS

CECR2 and BPTF/FALZ inhibitor

Key Product Details

Description:	CECR2 and BPTF/FALZ inhibitor
Chemical Name:	N-[(3-(1H)-Pyrazol-1-yl)propyl)-6-(4-(3-(dimethylamino)propoxy)phenyl)-2-(methylsulfonyl)pyrimidin-4-amine hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	495.04

View Full Technical Details for TP 238

Technical Data
Citations

Biological Activity for TP 238

TP 238 is a cat eye syndrome chromosome region, candidate 2 (CECR2) and bromodomain PHD finger transcription factor (BPTF/FALZ) inhibitor (IC₅₀ values are 10-30 and 100-350 nM, respectively).

A concentration of no more than 2 μM is recommended for use in cellular assays.

Licensing Information

This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the TP 238 probe summary on the SGC website.

Compound Libraries for TP 238

TP 238 is also offered as part of the Tocriscreen 2.0 Max and Tocriscreen Epigenetics Library. Find out more about compound libraries available from Tocris.

Technical Data for TP 238

M. Wt	495.04
Formula	C₂₂H₃₀N₆Osub>3S.HCl
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	2415263-05-5
Smiles	O=S(C1=NC(NCCCN2N=CC=C2)=CC(C3=CC=C(C=C3)OCCCN(C)C)=N1)(C)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for TP 238

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	49.5	100
	water	49.5	100

Preparing Stock Solutions for TP 238

The following data is based on the product molecular weight 495.04.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.02 mL	10.10 mL	20.20 mL
5 mM	0.40 mL	2.02 mL	4.04 mL
10 mM	0.20 mL	1.01 mL	2.02 mL
50 mM	0.04 mL	0.20 mL	0.40 mL

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Reconstitution Calculator

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Product Documents for TP 238

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.