TC E3 5032
Tocris Bioscience, part of Bio-Techne | Catalog # 6628
Precursor to Pomalidomide-based PROTACs
Discontinued Product
6628 has been discontinued.
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Key Product Details
Description
Precursor to Pomalidomide-based PROTACs
Product Description
TC E3 5032 is a functionalized cereblon ligand for PROTAC® research and development. Precursor to Pomalidomide (Cat.No. 6302) -based PROTACs. Incorporates a fluoro leaving group to allow conjugation to amine linker. Part of a range of functionalized tool molecules for PROTAC R&D.Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage Guidelines
This product is provided for use in onward chemistry. Suitable solvents can be used.Product Specifications
Molecular Weight
276.22
Formula
C13H9FN2O4
Storage
Store at +4°C
Purity
≥98% (HPLC)
Chemical Name
2-(2,6-Dioxo-3-piperidinyl)-4-fluoro-1H-isoindole-1,3(2H)-dione
CAS Number
835616-60-9
PubChem ID
11859051
InChI Key
CRAUTELYXAAAPW-UHFFFAOYSA-N
SMILES
O=C(C1=C(C=CC=C1C2=O)F)N2C3CCC(NC3=O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Molarity Calculator
Dilution Calculator
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Background References
References are publications that support the biological activity of the product.
- Remillard Degradation of the BAF complex factor BRD9 by heterobifunctional ligands. Angew.Chem.Int.Ed.Engl. 2017 PMID: 28418626
Product Specific Notices for TC E3 5032
For research use only
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