Taltirelin

Name: Taltirelin
Brand: Tocris Bioscience
SKU: 2672
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 2672

(1)

Citations (3)

COA / SDS

Synthetic thyrotropin-releasing hormone analog

Discontinued Product

2672 has been discontinued. View all Thyrotropin-Releasing Hormone Receptor Agonists products.

Key Product Details

Description:	Synthetic thyrotropin-releasing hormone analog
Alternative Names:	TA 0910
Chemical Name:	N-[[(4S)-Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl]carbonyl]-L-histidyl-L-prolinamide
Purity:	≥96% (HPLC)
Molecular Weight:	405.41

View Full Technical Details for Taltirelin

Technical Data
Citations / Reviews (1)

Biological Activity for Taltirelin

Taltirelin is a synthetic thyrotropin-releasing hormone (TRH) analog. Displays ~ 30 - 100-fold more potent CNS activity and ~ 50-fold weaker endocrine activity than TRH. Antinociceptive and neuroprotective.

Technical Data for Taltirelin

M. Wt	405.41
Formula	C₁₇H₂₃N₇O₅
Storage	Store at -20°C
Purity	≥96% (HPLC)
CAS Number	103300-74-9
PubChem ID	114750
InChi Key	LQZAIAZUDWIVPM-SRVKXCTJSA-N
Smiles	CN(C(C[C@@H]([C@@](N[C@@H](CC3=CNC=N3)C(N2[C@H]([C@](N)=O)CCC2)=O)=O)N1)=O)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for Taltirelin

References are publications that support the biological activity of the product.

Urayama Neuroprotective effect and brain receptor binding of taltirelin, a novel thyrotropin-releasing hormone (TRH) analogue, in transient forebrain ischemia of C57BL/6J mice. Life Sci. 2002 PMID: 12467901
Tanabe The synthetic TRH analogue taltirelin exerts modality-specific antinociceptive effects via distinct descending monoaminergic systems. Br.J.Pharmacol. 2007 PMID: 17220907
Suzuki Synthesis and central nervous system actions of thyrotropin-releasing hormone analogues containing a dihydroorotic acid moiety. J.Med.Chem. 1990 PMID: 2115588

Taltirelin

Tocris Bioscience, part of Bio-Techne | Catalog # 2672

Key Product Details

Biological Activity for Taltirelin

Technical Data for Taltirelin

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for Taltirelin

Product Documents for Taltirelin

COA

Certificate of Analysis

SDS

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