SUN 11602
Tocris Bioscience, part of Bio-Techne | Catalog # 4826
Basic fibroblast growth factor (bFGF) mimetic; neuroprotective
Discontinued Product
4826 has been discontinued.
View all Additional FGF Receptor Compounds products.
Key Product Details
Description
Basic fibroblast growth factor (bFGF) mimetic; neuroprotective
Product Description
SUN 11602 is a basic fibroblast growth factor (bFGF) mimetic. Mimics the neuroprotective effects of bFGF; prevents glutamate-induced neuronal death. Increases levels of CALB1 gene expression in cerebrocortical neurons. Triggers phosphorylation of FGFR, ERK1 and ERK2.Product Specifications
Molecular Weight
451.61
Formula
C26H37N5O2
Storage
Store at -20°C
Purity
≥98% (HPLC)
Chemical Name
4-[[4-[[2-[(4-Amino-2,3,5,6-tetramethylphenyl)amino]acetyl]methylamino]-1-piperidinyl]methyl]benzamide
CAS Number
704869-38-5
PubChem ID
22245705
InChI Key
KCODNOOPOPTZMO-UHFFFAOYSA-N
SMILES
NC1=C(C)C(C)=C(NCC(N(C)C2CCN(CC3=CC=C(C(N)=O)C=C3)CC2)=O)C(C)=C1C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 22.58 | 50 | |
| Ethanol | 9.03 | 20 |
Preparing Stock Solutions
for SUN 11602
The following data is based on the product molecular weight 451.61
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 4.43 mL | 22.14 mL | 44.29 mL |
| 2.5 mM | 0.89 mL | 4.43 mL | 8.86 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.43 mL |
| 25 mM | 0.09 mL | 0.44 mL | 0.89 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Murayama SUN11602, a novel aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. ACS Chem.Neurosci. 2013 PMID: 23421678
Product Specific Notices for SUN 11602
For research use only
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